用于治疗胃肠道疾病的药物的临床药代动力学（第二部分）。
Clinical pharmacokinetics of drugs used in the treatment of gastrointestinal diseases (Part II).
作者信息
Lauritsen K, Laursen L S, Rask-Madsen J
机构信息
Department of Medical Gastroenterology, Odense University Hospital, Denmark.
出版信息
Clin Pharmacokinet. 1990 Aug;19(2):94-125. doi: 10.2165/00003088-199019020-00002.
Part I of this article, which appeared in the previous issue of the Journal, covered the following agents: histamine H2-receptor antagonists (cimetidine, ranitidine, famotidine, nizatidine); muscarinic-M1-receptor antagonists (pirenzepine); proton pump inhibitors (omeprazole); site-protective agents (colloidal bismuth subcitrate, sucralfate); antacids and prostaglandin analogues; antiemetics and prokinetics (metoclopramide, domperidone, cisapride); and antispasmodics. In Part II, we consider the anti-inflammatory salicylates, nonspecific antidiarrhoeal agents, laxatives and cathartics.
本文的第一部分发表于上一期《杂志》，涵盖了以下药物：组胺H2受体拮抗剂（西咪替丁、雷尼替丁、法莫替丁、尼扎替丁）；毒蕈碱M1受体拮抗剂（哌仑西平）；质子泵抑制剂（奥美拉唑）；胃黏膜保护剂（枸橼酸铋钾、硫糖铝）；抗酸剂和前列腺素类似物；止吐药和促动力药（甲氧氯普胺、多潘立酮、西沙必利）；以及解痉药。在第二部分中，我们将探讨抗炎性水杨酸盐类、非特异性止泻药、泻药和导泻药。
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