Sharma A, Shrestha S, Upadhyay S, Rijal P
Department of Pediatrics, Nepal Medical College, Kathmandu, Nepal.
Nepal Med Coll J. 2011 Mar;13(1):24-6.
The aim of this study was to study the clinical and bacteriological profile of urinary tract infection (UTI) in children. This was a prospective study of 40 culture positive cases of UTI in children who attended pediatric outpatient department of Nepal Medical College Teaching Hospital. UTI was more common in female (65.0%) than in male (35.0%). Half were in the age group 1- 5 years. Fever was the most common presentation (65.0%) followed by abdominal pain (42.5%), decreased appetite (37.5%) and dysuria (37.5%). Escherichia coli was the most common (67.5%) bacterial isolate followed by Klebsiella sps (20.0%) and Proteus sps (10.0%). E. coli was 100 % sensitive to nitrofurantoin. E. coli was also highly sensitive to ofloxacin, cefotaxim and amikacin (94.0%). Klebsiella was 100 % sensitive to ciprofloxacin and amikacin. Greater degree of resistance was seen to ampicillin, cotrimoxazole and nalidixic acid.
本研究旨在探讨儿童尿路感染（UTI）的临床和细菌学特征。这是一项对尼泊尔医学院教学医院儿科门诊就诊的40例UTI培养阳性患儿进行的前瞻性研究。UTI在女性中（65.0%）比男性中（35.0%）更常见。一半患儿年龄在1至5岁之间。发热是最常见的症状（65.0%），其次是腹痛（42.5%）、食欲减退（37.5%）和排尿困难（37.5%）。大肠埃希菌是最常见的（67.5%）分离菌株，其次是克雷伯菌属（20.0%）和变形杆菌属（10.0%）。大肠埃希菌对呋喃妥因100%敏感。大肠埃希菌对氧氟沙星、头孢噻肟和阿米卡星也高度敏感（94.0%）。克雷伯菌对环丙沙星和阿米卡星100%敏感。对氨苄西林、复方新诺明和萘啶酸的耐药程度更高。
