术前系统阿片类药物需求、鞘内试验剂量和非心理因素作为鞘内泵治疗结果的预测因素：一位临床医生在腰椎后路减压术后疼痛方面的经验。
Role of pretrial systemic opioid requirements, intrathecal trial dose, and non-psychological factors as predictors of outcome for intrathecal pump therapy: one clinician's experience with lumbar postlaminectomy pain.
机构信息
Department of Anesthesiology, Henry Ford Hospital, Detroit, MI 48202, USA.
出版信息
Neuromodulation. 2011 Mar-Apr;14(2):165-75; discussion 175. doi: 10.1111/j.1525-1403.2011.00333.x. Epub 2011 Mar 1.
OBJECTIVE
Non-psychological parameters may predict pump success.
METHODS
Review was performed on 35 implants for gender, age, pretrial/trial dose, baseline visual analog scale (VAS), and pain location. One-year outcomes were % change VAS/intrathecal dose and medication change. Spearman coefficients correlated pretrial/trial dose, age, baseline VAS, and % change in VAS/intrathecal dose. Wilcoxon Rank-Sum tests correlated gender/pain location and % change in VAS/intrathecal dose. Pretrial/trial dose, baseline VAS, and medication change was tested using Wilcoxon Rank-Sums. Chi-square was used to correlate medication change with gender/pain location. A two-sample t-test compared age and medication change.
RESULTS
Positive correlation between % change VAS and trial dose was noted. Greater age correlated with lower VAS and % dose change. Marginally significant difference in % dose change by pain location was present with higher doses for leg pain.
CONCLUSION
Trial dose, age, and partially pain location are good predictors of pain relief.
目的
非心理参数可能预测泵的成功。
方法
对 35 例植入物进行了性别、年龄、术前/试验剂量、基线视觉模拟评分（VAS）和疼痛部位的回顾。一年的结果是 VAS/鞘内剂量的变化百分比和药物变化。Spearman 系数相关术前/试验剂量、年龄、基线 VAS 和 VAS/鞘内剂量的变化百分比。Wilcoxon 秩和检验相关性别/疼痛部位和 VAS/鞘内剂量的变化百分比。使用 Wilcoxon 秩和检验对术前/试验剂量、基线 VAS 和药物变化进行测试。卡方检验用于比较药物变化与性别/疼痛部位的关系。两样本 t 检验比较年龄和药物变化。
结果
VAS 的变化百分比与试验剂量呈正相关。年龄越大，VAS 和剂量变化百分比越低。腿部疼痛的疼痛部位的剂量变化百分比有显著差异，剂量较高。
结论
试验剂量、年龄和部分疼痛部位是疼痛缓解的良好预测指标。
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