Department of Anesthesiology and Pain Medicine, University of Texas Medical Branch, Galveston, TX, USA.
J Pain Res. 2014 Oct 3;7:571-7. doi: 10.2147/JPR.S46929. eCollection 2014.
The management of chronic pain can be very challenging. Often, physicians employ intrathecal (IT) drug delivery systems as a last resort to relieve intractable pain. The system consists of an implantable pump that stores and delivers medication through a catheter to the IT space. Programmability is achieved by positioning an external devise over the implanted pump to change the mode of drug delivery. The innovations in programmable IT drug delivery systems are expanding more rapidly than ever before. Unfortunately, the rapid expansion is accompanied by a lack of prospective randomized trials examining these new options. In an effort to improve results and reduce side effects, publications by experts or expert consensus panels provide guidance for the community. The purpose of this article is to provide a summary of high interest topics in recent publications.
慢性疼痛的管理极具挑战性。通常,医生会将鞘内(IT)药物输送系统作为缓解难治性疼痛的最后手段。该系统包括一个可植入的泵,通过导管将药物储存在其中并输送到 IT 空间。通过将外部设备放置在植入式泵上来改变药物输送模式,从而实现可编程性。可编程 IT 药物输送系统的创新比以往任何时候都发展得更快。不幸的是,快速扩张伴随着缺乏前瞻性随机试验来检查这些新选择。为了提高疗效和减少副作用,专家或专家共识小组的出版物为社区提供了指导。本文的目的是总结近期出版物中一些热门话题。