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肠道微生态与健康。

Intestinal microecology in health and wellness.

机构信息

Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT 06510, USA.

出版信息

J Clin Gastroenterol. 2011 Nov;45 Suppl:S108-10. doi: 10.1097/MCG.0b013e3182309276.

Abstract

Intestinal microecology consists of 4 components-the luminal gastrointestinal tract, secretions of the tract, the epithelium, nutrients and foods that enter the tract, and the microbatome or microflora. This ecosystem is very dynamic. It is not possible to define a normal flora as it varies with geography, diet, and the dynamics of the microecology. A normal flora exists in a healthy human. The life cycle of the intestinal microbatome will vary with geography and feeding. Dysbiosis may occur in disease. At the present time, the flora is best determined from older biochemical techniques and newer genetic bacteriologic studies, but much more research is needed to define the makeup of the microbatome as it varies with diet and geography.

摘要

肠道微生态由 4 个部分组成——腔胃肠道、分泌物、上皮、进入腔道的营养物质和食物,以及微生物组或微生物群。这个生态系统非常动态。由于地理、饮食和微生态的动态变化,不可能定义正常菌群。正常菌群存在于健康的人体中。肠道微生物组的生命周期将因地理和喂养方式而有所不同。在疾病中可能会发生菌群失调。目前,菌群最好通过较老的生化技术和较新的遗传细菌学研究来确定,但需要进行更多的研究来确定随着饮食和地理变化的微生物组的组成。

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