Ruml T, Silhánková L
Department of Biochemistry and Microbiology, Institute of Chemical Technology, Prague.
Folia Microbiol (Praha). 1990;35(2):168-71. doi: 10.1007/BF02820775.
A dominant mutation, responsible for the resistance to oxythiamin in Saccharomyces cerevisiae was mapped on the right arm of chromosome IV, 4.6 cM centromere-distally to trp1. The corresponding gene is not involved in the control of intracellular content of total thiamin during growth on a minimal medium without thiamin.
一个导致酿酒酵母对氧硫胺产生抗性的显性突变被定位在第四条染色体右臂上,距trp1基因着丝粒远端4.6厘摩处。在不含硫胺素的基本培养基上生长时,相应基因不参与总硫胺素细胞内含量的调控。