Iwashima A, Yoshioka K, Nishimura H, Nosaka K
Experientia. 1984 Jun 15;40(6):582-3. doi: 10.1007/BF01982343.
Oxythiamine reversed the growth inhibition of Saccharomyces cerevisiae caused by pyrithiamine, although oxythiamine alone inhibited yeast cell growth. This phenomenon was explained by thiamine production from these 2 thiamine antagonists which was demonstrated using cell suspensions and the crude extract of S. cerevisiae.
氧硫胺逆转了由吡硫胺引起的酿酒酵母生长抑制,尽管单独使用氧硫胺会抑制酵母细胞生长。这一现象可通过这两种硫胺拮抗剂产生硫胺来解释,这已通过使用细胞悬浮液和酿酒酵母粗提物得到证实。