Bartenjev Igor, Oremović Lenka, Rogl Butina Mirjam, Sjerobabski Masnec Ines, Bouloc Anne, Voda Karmen, Šitum Mirna
Dermatologija Bartenjev-Rogl, Ljubljana, Slovenia.
Acta Dermatovenerol Alp Pannonica Adriat. 2011 Jun;20(2):55-62.
Physiological acne is a milder form of clinical acne and is very frequent in adult women (18 years of age and older). Acne therapy is usually unnecessary in such cases, and so appropriate cosmetic treatments are sought.
To determine the effectiveness of a topical cosmetic hydrating skincare treatment for adult acne-prone skin (Normaderm, Vichy, France) against the clinical signs of physiological acne: few inflammatory and retentional lesions, uneven (grainy) skin relief, dilated pores, and occasional and/or local hyperseborrhea.
Within the study, the tested product's keratolytic, antimicrobial, and antiseborrheic properties, and its overall ability to improve the clinical signs of physiological acne present in adult subjects were evaluated through objective and clinical evaluation methods by the investigators and through self-evaluation questionnaires by the subjects themselves. The study group was composed of 50 adult women between 18 and 35 years of age with combination or oily acne-prone skin, who were chosen according to previously defined inclusion criteria. They applied the product tested twice daily on thoroughly cleansed skin for a period of 2 months. The results were evaluated after 30 (±2) and 60 (±2) days.
The number of inflammatory and retentional lesions on the forehead, cheeks, and chin decreased after 60 days of use (an average of 30.7% and 70.7%, respectively). The level of sebum secretion on the forehead decreased by 33.4% and the level of skin scaling decreased by 38.5% after 60 days of use. The moisture content in the horny layer on the forehead, cheeks, and chin increased by an average 39.7%. The decrease in pore size and content after 60 days of use was very noticeable. The subjects evaluated all the studied characteristics of the product tested very positively, with results already showing after 30 days of use.
The results of the study confirm that the product tested is suitable for the cosmetic care of adult acne-prone skin, either as an independent cosmetic hydrating skincare treatment, as a complementary cosmetic part of acne therapy, or as a subsequent cosmetic regimen to sustain the results of the acne therapy for a longer period of time.
生理性痤疮是临床痤疮的一种较轻形式,在成年女性(18岁及以上)中非常常见。在这种情况下通常无需进行痤疮治疗,因此人们寻求合适的美容治疗方法。
确定一种用于成人易长痤疮皮肤的外用美容保湿护肤疗法(法国薇姿Normaderm)对生理性痤疮临床症状的疗效:炎症性和潴留性皮损较少、皮肤纹理不均(粗糙)、毛孔粗大以及偶尔和/或局部皮脂溢出。
在该研究中,研究人员通过客观和临床评估方法以及受试者自身的自我评估问卷,评估了受试产品的角质溶解、抗菌和抗脂溢特性,及其改善成年受试者生理性痤疮临床症状的总体能力。研究组由50名年龄在18至35岁之间、皮肤为混合性或油性且易长痤疮的成年女性组成,她们是根据先前定义的纳入标准挑选出来的。她们每天在彻底清洁的皮肤上涂抹受试产品两次,持续2个月。在30(±2)天和60(±2)天后评估结果。
使用60天后,前额、脸颊和下巴上的炎症性和潴留性皮损数量减少(分别平均减少30.7%和70.7%)。使用60天后,前额的皮脂分泌水平下降了33.4%,皮肤脱屑水平下降了38.5%。前额、脸颊和下巴角质层的水分含量平均增加了39.7%。使用60天后,毛孔大小和含量的减小非常明显。受试者对受试产品的所有研究特性评价都非常积极,使用30天后就已见成效。
研究结果证实,受试产品适用于成人易长痤疮皮肤的美容护理,既可以作为独立的美容保湿护肤疗法,作为痤疮治疗的辅助美容部分,也可以作为后续的美容方案,以在更长时间内维持痤疮治疗的效果。