Department of Acupuncture and Moxibustion, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
Chin J Integr Med. 2012 Jan;18(1):48-55. doi: 10.1007/s11655-011-0861-5. Epub 2011 Oct 12.
To assess the clinical evidence for and against acupuncture as a treatment for Bell's palsy.
We conducted a literature search of 15 databases from their inception to December 2010 without language restrictions. We included all randomized clinical trials (RCTs) regardless of their controls. Methodological quality was evaluated using the Cochrane risk of bias assessment tool.
Of the 3 474 articles, only eight RCTs met our inclusion criteria. Four RCTs tested the effects of acupuncture against drug therapy on disease response rate. The meta-analysis of these data showed significant improvements in the acupuncture group [n=463, risk ratio (RR)=1.07, 95% CI: 1.02 to 1.13; P=0.006, I(2)=0%]. Six RCTs tested the effects of acupuncture plus drug therapy versus drug therapy alone. The meta-analysis of this set of RCTs also showed the favorable effects of acupuncture on disease response rate (n=512, RR=1.11, 95% CI: 1.05 to 1.17; P=0.001, I(2)=13%).
The evidence supporting the effectiveness of acupuncture for treating Bell's palsy is limited. The number and quality of trials are too low to form firm conclusions. Further rigorous RCTs are warranted but need to overcome the many limitations of the current evidence.
评估针刺治疗贝尔氏面瘫的临床证据。
我们对 15 个数据库进行了文献检索,检索时间从建库到 2010 年 12 月,没有语言限制。我们纳入了所有随机临床试验(RCT),无论其对照如何。使用 Cochrane 偏倚风险评估工具评估方法学质量。
在 3474 篇文章中,只有 8 项 RCT 符合我们的纳入标准。4 项 RCT 测试了针刺与药物治疗对疾病反应率的影响。这些数据的荟萃分析显示针刺组有显著改善[n=463,风险比(RR)=1.07,95%可信区间:1.02 至 1.13;P=0.006,I(2)=0%]。6 项 RCT 测试了针刺加药物治疗与单独药物治疗的效果。这组 RCT 的荟萃分析也显示了针刺对疾病反应率的有利影响(n=512,RR=1.11,95%可信区间:1.05 至 1.17;P=0.001,I(2)=13%)。
支持针刺治疗贝尔氏面瘫有效的证据有限。试验的数量和质量都太低,无法得出明确的结论。需要进一步进行严格的 RCT,但需要克服当前证据的许多局限性。