多重任务：充分利用逆转录病毒包膜
Multitasking: Making the Most out of the Retroviral Envelope.
机构信息
Department of Veterinary Medicine, University of Cambridge, Madingley Road, CB3 0ES, Cambridge, England, UK.
Medical Research Council - University of Glasgow Centre for Virus Research, Institute for Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Scotland, UK.
出版信息
Viruses. 2010 Aug;2(8):1571-1576. doi: 10.3390/v2081571. Epub 2010 Aug 2.
Evasion of the host's immune system is a required step for the establishment of viral infection. In this article, we discuss the recent findings of Heidmann and colleagues demonstrating that some retroviruses possess an immune suppressive (IS) domain "encrypted" within their envelope glycoprotein that is required to establish a successful infection in immunocompetent hosts [1].
逃避宿主的免疫系统是病毒感染建立所必需的步骤。在本文中，我们讨论了 Heidmann 及其同事的最新发现，表明一些逆转录病毒在其包膜糖蛋白内具有一个免疫抑制（IS）结构域，该结构域是在免疫功能正常的宿主中建立成功感染所必需的[1]。
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