对来自接种传染性法氏囊病病毒疫苗的母禽的雏鸡接种传染性法氏囊病病毒疫苗。
Infectious bursal agent vaccination of chicks from infectious bursal agent-vaccinated dams.
作者信息
Ide P R
出版信息
Can Vet J. 1979 Feb;20(2):35-40.
Chicks from infectious bursal agent-vaccinated broiler breeders were vaccinated with a commercial infectious bursal agent vaccine at intervals after hatching. Bursas from some of these chicks were examined for infectious bursal agent-specific fluorescence four days after vaccination and bursas from others were examined for histological lesions of infectious bursal disease 21 days after vaccination. Serological studies were conducted to determine if active immunity to infectious bursal agent followed vaccination. Chicks failed to develop immunity if their levels of maternally-derived serum neutralizing antibody were in excess of approximately log(2) 7 at the time of vaccination. When antibody titres fell below this level, vaccination usually resulted in infectious bursal agent virus replication in the bursa and consequential bursal damage but was followed by development of active immunity.
来自接种传染性法氏囊病病原体疫苗的肉种鸡的雏鸡在孵化后每隔一段时间接种一种商用传染性法氏囊病病原体疫苗。其中一些雏鸡的法氏囊在接种疫苗后4天进行传染性法氏囊病病原体特异性荧光检查，另一些雏鸡的法氏囊在接种疫苗后21天进行传染性法氏囊病组织学损伤检查。进行血清学研究以确定接种疫苗后是否产生了对传染性法氏囊病病原体的主动免疫。如果雏鸡在接种疫苗时母源血清中和抗体水平超过约log(2) 7，则无法产生免疫力。当抗体滴度降至该水平以下时，接种疫苗通常会导致传染性法氏囊病病毒在法氏囊中复制并进而造成法氏囊损伤，但随后会产生主动免疫。
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