评估Directigen 1,2,3 A组链球菌检测用于诊断链球菌性咽炎的效果。
Evaluation of the Directigen 1,2,3 Group A Strep Test for diagnosis of streptococcal pharyngitis.
作者信息
Moyer N P, Quinn P J, Showalter C A
机构信息
Hygienic Laboratory, University of Iowa, Iowa City 52242.
出版信息
J Clin Microbiol. 1990 Jul;28(7):1661-3. doi: 10.1128/jcm.28.7.1661-1663.1990.
Abstract
The Directigen 1,2,3 Group A Strep Test (DGAST; BBL Microbiology Systems, Cockeysville, Md.) was compared with conventional culture methods for the detection of group A streptococci. Among 327 children, the DGAST has a sensitivity of 75.0%, a specificity of 99.1%, and positive and negative predictive values of 97.5 and 89.3%, respectively, as compared with 48-h culture results. The lower sensitivity (60.0%) in 322 adults was related to the low incidence of group A streptococcal pharyngitis in that population (7.8%). The positive and negative predictive values for adults were 93.8 and 96.7%, respectively. Only 3 of 327 (0.9%) pediatric and 2 of 322 (0.6%) adult specimens yielded uninterpretable results in the DGAST.
摘要
将Directigen 1,2,3 A组链球菌检测试验（DGAST；BBL微生物系统公司，马里兰州科基斯维尔）与检测A组链球菌的传统培养方法进行了比较。在327名儿童中，与48小时培养结果相比，DGAST的灵敏度为75.0%，特异性为99.1%，阳性预测值和阴性预测值分别为97.5%和89.3%。在322名成年人中，较低的灵敏度（60.0%）与该人群中A组链球菌性咽炎的低发病率（7.8%）有关。成年人的阳性预测值和阴性预测值分别为93.8%和96.7%。在DGAST中，327份儿科标本中只有3份（0.9%）、322份成人标本中只有2份（0.6%）产生了无法解读的结果。
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