两种快速链球菌抗原检测方法与培养法在诊断链球菌性咽炎中的比较。
Comparison of two rapid streptococcal antigen detection assays with culture for diagnosis of streptococcal pharyngitis.
作者信息
Heiter B J, Bourbeau P P
机构信息
Division of Laboratory Medicine, Geisinger Medical Center, Danville, Pennsylvania 17822, USA.
出版信息
J Clin Microbiol. 1995 May;33(5):1408-10. doi: 10.1128/jcm.33.5.1408-1410.1995.
Abstract
In this study, 801 pharyngeal specimens were cultured for group A streptococci and tested with the Biostar Strep A Optical Immunoassay (Strep A OIA). The respective sensitivities and specificities were as follows: culture, 97.1 and 100%; Strep A OIA, 91.5 and 94.8%. Of the 801 specimens, 597 were also tested with the Abbott TestPack Strep A Assay (TP-ST). For those specimens tested by all three methods, the respective sensitivities and specificities were as follows: culture, 98.1 and 100%; Strep A OIA, 92.3 and 95.4%; and TP-ST, 79.4 and 100%. The Strep A OIA is significantly more sensitive than TP-ST and compares favorably with culture.
摘要
在本研究中，对801份咽拭子标本进行了A组链球菌培养，并采用Biostar A群链球菌光学免疫测定法（A群链球菌OIA）进行检测。各自的敏感性和特异性如下：培养法，97.1%和100%；A群链球菌OIA，91.5%和94.8%。在801份标本中，有597份还采用雅培A群链球菌检测试剂盒（TP-ST）进行了检测。对于所有三种方法都检测的那些标本，各自的敏感性和特异性如下：培养法，98.1%和100%；A群链球菌OIA，92.3%和95.4%；TP-ST，79.4%和100%。A群链球菌OIA比TP-ST明显更敏感，与培养法相比也具有优势。
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