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Hypothalamic-pituitary-adrenal axis suppression related to topical glucocorticoid therapy in a child with psoriatic exfoliative erythroderma.

作者信息

Campbell Lauren S, Chevalier Michelle, Levy Richard A, Rhodes Arthur

机构信息

Department of Dermatology, Rush University Medical Center, Chicago, Illinois 60612, USA.

出版信息

Pediatr Dermatol. 2012 Jan-Feb;29(1):101-4. doi: 10.1111/j.1525-1470.2011.01471.x. Epub 2011 Oct 13.

DOI:10.1111/j.1525-1470.2011.01471.x
PMID:21995486
Abstract

Exfoliative erythroderma is a rare presentation of psoriasis in children and adults. We report a 9-year-old girl with exfoliative erythroderma secondary to plaque-type psoriasis who developed hypothalamic-pituitary-adrenal axis suppression resulting from topical treatment with a medium-potency glucocorticoid. This case emphasizes the need for awareness of this potentially life-threatening complication of topical glucocorticoid use, particularly in patients who have significant compromise of barrier function secondary to widespread skin disease.

摘要

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