利用行政索赔数据进行类风湿关节炎治疗的比较效果研究。
Use of administrative claims data for comparative effectiveness research of rheumatoid arthritis treatments.
出版信息
Arthritis Res Ther. 2011;13(5):129. doi: 10.1186/ar3472. Epub 2011 Oct 7.
Abstract
Observational studies, particularly those using large administrative claims databases, have become increasingly popular sources of comparative effectiveness or comparative safety research. Studies using claims data often face challenges and criticisms due to the lack of certain clinical information, such as lifestyle risk factors, disease severity, and questionable accuracy of disease diagnoses. A novel, claims-based algorithm to evaluate the clinical effectiveness of rheumatoid arthritis medications has been developed and its performance seems promising, although further validation is needed.
摘要
观察性研究，特别是那些使用大型行政索赔数据库的研究，已经成为比较有效性或比较安全性研究的越来越受欢迎的来源。由于缺乏某些临床信息，例如生活方式风险因素、疾病严重程度和疾病诊断的准确性值得怀疑，因此使用索赔数据的研究经常面临挑战和批评。已经开发出一种新颖的、基于索赔的算法来评估类风湿关节炎药物的临床效果，其性能似乎很有希望，尽管还需要进一步验证。
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