CNRS, IPBS (Institut de Pharmacologie et de Biologie Structurale), 205 route de Narbonne, F-31077 Toulouse, France.
Int J Pharm. 2012 Feb 14;423(1):3-6. doi: 10.1016/j.ijpharm.2011.09.038. Epub 2011 Oct 1.
Electro-permeabilisation allows the free access of polar compounds to the cytoplasm by a reversible alteration of the cell membrane. It is now used in clinics for the eradication of cutaneous solid tumors. New developments predict its future applications for other anti-cancer treatments.
电穿孔通过可逆地改变细胞膜使极性化合物自由进入细胞质。目前,它被用于临床以消除皮肤实体肿瘤。新的发展预示着它未来在其他抗癌治疗中的应用。