Riabinin V A, Golikov A P
Kardiologiia. 1990 Mar;30(3):13-7.
A method for computed determination of death probability was used to examine the effects of various modalities of stress-limiting therapy on mortality rates within a month after myocardial infarction. The examination was made in 591 patients with large myocardial infarction. A significant decrease in mortality rates was seen in patients on finoptin and phosphocreatine (by 9.6 and 11.2, respectively) as compared to the expected drop. Other agents given within the first hours of myocardial infarction such as beta-blockers, opioid peptides, sodium oxybutyrate, piracetam, antioxidants were demonstrated to cause no reduction in mortality rates.
采用一种计算死亡概率的方法,研究了各种应激限制疗法对心肌梗死后1个月内死亡率的影响。对591例大面积心肌梗死患者进行了检查。与预期下降相比,使用芬诺替丁和磷酸肌酸的患者死亡率显著下降(分别下降9.6和11.2)。在心肌梗死最初几小时内给予的其他药物,如β受体阻滞剂、阿片肽、羟丁酸钠、吡拉西坦、抗氧化剂,未显示能降低死亡率。