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电子 von Frey 和 von Frey 单丝测试的可重复性。

Reproducibility of Electronic Von Frey and Von Frey monofilaments testing.

机构信息

Department of Anesthesiology, Hospital Clinic, University of Barcelona, Barcelona, Spain.

出版信息

Clin J Pain. 2012 May;28(4):318-23. doi: 10.1097/AJP.0b013e31822f0092.

Abstract

OBJECTIVES

Von Frey monofilaments (VFM) and Electronic von Frey are used as quantitative sensory testing to explore mechanical hyperalgesia. The aim of the study was to determine VFM and Electronic von Frey reproducibility and the time required for testing undamaged areas in volunteers and surgical in-hospital patients.

METHODS

Prospective study in 2 groups of individuals without neurological disorders and not receiving treatments that alter sensorial response. Group 1 was formed by 30 healthy volunteers and group 2 by 28 patients after knee arthroplasty who received unilateral femoral block as postoperative analgesia. Testing was performed by 2 trained investigators in the forearm and abdominal wall and repeated 24 hours later. Pain threshold was determined as the VMF or the pressure rate applied with the Electronic von Frey referred to as unpleasant. The time used in each test was measured. Intraobserver and interobserver reproducibility were analyzed by means of Kappa and Lin coefficients.

RESULTS

Intraobserver and interobserver reproducibility for VFM was only fair or moderate in both groups (Kappa<0.6). Intraobserver reproducibility for Electronic von Frey was good in Group 1 (Lin 0.61 to 0.8) and almost perfect in Group 2 (Lin>0.8). No differences were found between the 2 tested areas. Time used was 6.03 and 3.16 minutes for VFM and Electronic von Frey, respectively.

DISCUSSION

Exploration of mechanical allodynia in postoperative patients requires rapid and reliable quantitative sensory testing. Electronic von Frey was more reliable and rapid than VFM in exploring mechanical pain thresholds in undamaged areas in volunteers and patients. Further studies are required to confirm whether these results can be extrapolated to areas affected by surgery.

摘要

目的

Von Frey 单丝(VFM)和电子 Von Frey 用于定量感觉测试以探索机械性痛觉过敏。本研究的目的是确定 VFM 和电子 Von Frey 的可重复性以及在志愿者和手术住院患者中测试未受损区域所需的时间。

方法

对无神经疾病且未接受改变感觉反应的治疗的个体进行前瞻性研究。第 1 组由 30 名健康志愿者组成,第 2 组由 28 名接受单侧股神经阻滞作为术后镇痛的膝关节置换术后患者组成。由 2 名受过培训的研究人员在前臂和腹壁进行测试,并在 24 小时后重复测试。疼痛阈值被确定为 VMF 或电子 Von Frey 施加的压力率,被认为是不愉快的。测量每个测试中使用的时间。通过 Kappa 和 Lin 系数分析观察者内和观察者间的可重复性。

结果

在两组中,VFM 的观察者内和观察者间的可重复性仅为一般或中度(Kappa<0.6)。第 1 组中,电子 Von Frey 的观察者内可重复性良好(Lin 0.61 至 0.8),第 2 组中几乎完美(Lin>0.8)。在两个测试区域之间未发现差异。VFM 和电子 Von Frey 分别用时 6.03 分钟和 3.16 分钟。

讨论

术后患者机械性感觉过敏的探索需要快速可靠的定量感觉测试。在志愿者和患者的未受损区域中,电子 Von Frey 比 VFM 更可靠和快速地探索机械疼痛阈值。需要进一步的研究来确认这些结果是否可以外推到受手术影响的区域。

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