Amat Par P, Sanosa Valls J, Lluch Pérez M, Malet Casajuana A, García Calderón P A
Inmunolab, Barcelona, Spain.
Allergol Immunopathol (Madr). 1990 Jan-Feb;18(1):27-34.
A group of 102 patients (children and adults) with hypersensitivity to dried fruits and dermo-respiratory pathology underwent "in vivo" tests (skin tests) and "in vitro" tests (histamine release test, specific IgE) using a battery of foods and neumoallergens. We assessed immunoglobulin (IgG, IgA, IgM, IgE) levels as well as the complement (CH50), its components (C3, C4) and the possible presence of circulating immune complexes. Of the dried fruits the almond was the most sensitizing (89%, 87% and 68% of correlation between the clinical history and "in vivo" tests--skin tests--and "in vitro" tests--histamine release test and RAST--, respectively). As regards the other sensitizations, a hypersensitivity to peach was detected in 47% of the cases. As for the association between food allergy and pollen hypersensitivity, the highest percentages were for tree pollen (51%) followed by weeds (27%) and grasses (25%). The complement values did not show significant differences when they were compared with the control population. The statistical study correlating the clinical history with the results of the diagnostic methods--agreements between two or three tests--was positive (p greater than 0.05) for almond and peanut whereas it was negative (p less than 0.005) for hazelnut.
一组102名对干果过敏且患有皮肤呼吸疾病的患者（儿童和成人），使用一系列食物和呼吸道变应原进行了“体内”试验（皮肤试验）和“体外”试验（组胺释放试验、特异性IgE）。我们评估了免疫球蛋白（IgG、IgA、IgM、IgE）水平以及补体（CH50）、其成分（C3、C4）和循环免疫复合物的可能存在情况。在干果中，杏仁致敏性最强（临床病史与“体内”试验——皮肤试验——以及“体外”试验——组胺释放试验和放射性变应原吸附试验（RAST）——之间的相关性分别为89%、87%和68%）。至于其他致敏情况，47%的病例检测到对桃子过敏。关于食物过敏与花粉过敏之间的关联，树木花粉的比例最高（51%），其次是杂草（27%）和草类（25%）。与对照人群相比，补体值没有显示出显著差异。将临床病史与诊断方法的结果——两项或三项试验之间的一致性——进行相关性统计研究，杏仁和花生的结果为阳性（p>0.05），而榛子的结果为阴性（p<0.005）。
