• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

关节抽吸和皮质类固醇注射治疗膝骨关节炎的效果。

The effect of joint aspiration and corticosteroid injections in osteoarthritis of the knee.

机构信息

Western Hospital, Melbourne, Australia.

出版信息

Int J Rheum Dis. 2011 Oct;14(4):384-9. doi: 10.1111/j.1756-185X.2011.01631.x. Epub 2011 Aug 31.

DOI:10.1111/j.1756-185X.2011.01631.x
PMID:22004237
Abstract

AIM

To evaluate the benefits of knee joint aspiration and injection in knee osteoarthritis (OA).

METHODS

A retrospective, pilot study involved 110 patients with knee OA from a dedicated OA clinic in a Melbourne tertiary hospital from 2007 to 2009. Only those who had completed two Multiple Attribute Prioritization Tool (MAPT) questionnaires within 6 months of the initial review were included. The MAPT was designed to help prioritise patients on orthopedic waiting lists. Three groups were analyzed: patients who had no corticosteroid injection or aspiration, patients who received corticosteroid injections, and patients who received both joint aspiration with corticosteroid injections.

RESULTS

Patients who had both joint aspiration and injection reported an improvement in pain compared with those who had no injection (56.3%vs. 32.2%, P = 0.03). Those who had joint injections also did better than those without injection (62.7%vs. 32.2%, P = 0.001). Reduced analgesia use was noted in 12.5% of patients with aspiration and injection compared with 1.7% with no injection or aspiration (P = 0.03). Improved walking distance was noted in 22.4% of patients who had injections compared with 8.5% of patients with no injections (P = 0.03). No significant differences in MAPT scores among the different treatment groups were noted.

CONCLUSION

This pilot study appears to show a beneficial trend in giving corticosteroid injections and to aspirate the knee in OA patients. Further studies are needed to address the mechanical benefits, quadriceps strengthening and pain reduction with knee aspiration, as well as the effects that different volumes of fluid may have on knee mechanics and symptoms.

摘要

目的

评估膝关节抽吸和注射在膝骨关节炎(OA)中的益处。

方法

这是一项回顾性、试点研究,纳入了 2007 年至 2009 年期间墨尔本一家三级医院专门的 OA 诊所的 110 例膝 OA 患者。仅纳入了在初次就诊后 6 个月内完成了两次多属性优先排序工具(MAPT)问卷的患者。MAPT 旨在帮助对骨科等候名单上的患者进行优先排序。分析了三组患者:未接受皮质类固醇注射或抽吸的患者、接受皮质类固醇注射的患者和同时接受关节抽吸加皮质类固醇注射的患者。

结果

与未接受注射的患者相比,同时接受关节抽吸和注射的患者报告疼痛改善(56.3%对 32.2%,P=0.03)。接受关节注射的患者也比未接受注射的患者表现更好(62.7%对 32.2%,P=0.001)。与未接受注射或抽吸的患者(1.7%)相比,接受抽吸和注射的患者中有 12.5%的患者减少了镇痛药物的使用(P=0.03)。与未接受注射的患者(8.5%)相比,接受注射的患者中有 22.4%的患者行走距离改善(P=0.03)。不同治疗组之间的 MAPT 评分无显著差异。

结论

本试点研究似乎表明,在 OA 患者中给予皮质类固醇注射和抽吸膝关节有有益的趋势。需要进一步研究以确定膝关节抽吸的机械效益、股四头肌强化和疼痛减轻,以及不同容量的液体可能对膝关节力学和症状的影响。

相似文献

1
The effect of joint aspiration and corticosteroid injections in osteoarthritis of the knee.关节抽吸和皮质类固醇注射治疗膝骨关节炎的效果。
Int J Rheum Dis. 2011 Oct;14(4):384-9. doi: 10.1111/j.1756-185X.2011.01631.x. Epub 2011 Aug 31.
2
Efficacy of intra-articular botulinum toxin type A in painful knee osteoarthritis: a pilot study.关节内注射肉毒毒素 A 治疗膝关节骨关节炎疼痛的疗效:一项初步研究。
PM R. 2010 Apr;2(4):268-76. doi: 10.1016/j.pmrj.2010.02.011.
3
Increased joint loads during walking--a consequence of pain relief in knee osteoarthritis.行走过程中关节负荷增加——膝骨关节炎疼痛缓解的一个后果。
Knee. 2006 Dec;13(6):445-50. doi: 10.1016/j.knee.2006.08.005. Epub 2006 Sep 29.
4
A double blind, randomized, placebo controlled study to evaluate the efficacy of erythromycin in patients with knee effusion due to osteoarthritis.一项双盲、随机、安慰剂对照研究,旨在评估红霉素治疗骨性关节炎膝关节积液患者的疗效。
Int J Rheum Dis. 2009 Apr;12(1):44-51. doi: 10.1111/j.1756-185X.2009.01379.x.
5
Tolerability and short-term effectiveness of hylan G-F 20 in 4253 patients with osteoarthritis of the knee in clinical practice.玻璃酸钠G-F 20在4253例膝骨关节炎患者临床实践中的耐受性和短期疗效
Curr Med Res Opin. 2005 Aug;21(8):1261-9. doi: 10.1185/030079905X56501.
6
[Study on the effect of sodium hyaluronate intra-articular injection on the treatment of knee osteoarthritis].[透明质酸钠关节腔内注射治疗膝关节骨关节炎的疗效研究]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2005 Mar 15;19(3):210-4.
7
Outcomes of intra-articular injection of sodium hyaluronate for the treatment of osteoarthritis of the knee.关节腔内注射透明质酸钠治疗膝骨关节炎的疗效
J Med Assoc Thai. 2007 Sep;90(9):1845-52.
8
Comparison of intra-articular hyaluronic acid injections and mud-pack therapy in the treatment of knee osteoarthritis.关节内注射透明质酸与泥敷疗法治疗膝骨关节炎的比较。
Acta Orthop Traumatol Turc. 2010;44(1):42-7. doi: 10.3944/AOTT.2010.2238.
9
Hylan versus corticosteroid versus placebo for treatment of basal joint arthritis: a prospective, randomized, double-blinded clinical trial.透明质烷与皮质类固醇及安慰剂治疗拇指腕掌关节关节炎的前瞻性、随机、双盲临床试验
J Hand Surg Am. 2008 Jan;33(1):40-8. doi: 10.1016/j.jhsa.2007.10.009.
10
Pain relief in knee osteoarthritis reduces the propensity to trip on an obstacle.膝关节骨关节炎的疼痛缓解可降低在障碍物上绊倒的倾向。
Gait Posture. 2007 Jan;25(1):106-11. doi: 10.1016/j.gaitpost.2006.02.001. Epub 2006 Mar 10.

引用本文的文献

1
Efficacy of platelet-rich plasma and plasma for symptomatic treatment of knee osteoarthritis: a double-blinded placebo-controlled randomized clinical trial.富血小板血浆和血浆治疗膝关节骨关节炎症状的疗效:一项双盲安慰剂对照随机临床试验。
BMC Musculoskelet Disord. 2021 Sep 24;22(1):822. doi: 10.1186/s12891-021-04706-7.
2
Meta-analysis of pain relief effects by laser irradiation on joint areas.激光照射关节部位缓解疼痛效果的Meta分析。
Photomed Laser Surg. 2012 Aug;30(8):405-17. doi: 10.1089/pho.2012.3240. Epub 2012 Jun 29.