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新型概念色谱柱的设计。

The design of a new concept chromatography column.

机构信息

Australian Centre for Research on Separation Science, School of Natural Sciences, University of Western Sydney, NSW, Australia.

出版信息

Analyst. 2011 Dec 21;136(24):5127-30. doi: 10.1039/c1an15681k. Epub 2011 Oct 17.

DOI:10.1039/c1an15681k
PMID:22005770
Abstract

Active Flow Management is a new separation technique whereby the flow of mobile phase and the injection of sample are introduced to the column in a manner that allows migration according to the principles of the infinite diameter column. A segmented flow outlet fitting allows for the separation of solvent or solute that elutes along the central radial section of the column from that of the sample or solvent that elutes along the wall region of the column. Separation efficiency on the analytical scale is increased by 25% with an increase in sensitivity by as much as 52% compared to conventional separations.

摘要

主动流管理是一种新的分离技术,通过这种技术,流动相和样品的注入以允许根据无限直径柱原理进行迁移的方式引入到柱中。分段流出口配件允许从沿柱壁区域洗脱的样品或溶剂中分离出沿柱的中心径向部分洗脱的溶剂或溶质。与传统分离相比,分析规模的分离效率提高了 25%,灵敏度提高了多达 52%。

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