长期抗真菌治疗的球孢子菌病患者氟过量：目前可用的三唑类药物评估。
Fluoride excess in coccidioidomycosis patients receiving long-term antifungal therapy: an assessment of currently available triazoles.
机构信息
Department of Medical Microbiology and Immunology, Coccidioidomycosis Serology Laboratory, University of California—Davis, Davis, California, USA.
出版信息
Antimicrob Agents Chemother. 2012 Jan;56(1):563-4. doi: 10.1128/AAC.05275-11. Epub 2011 Oct 17.
Abstract
The use of voriconazole, a trifluorinated antifungal, has been associated with the development of fluoride excess and periostitis/exostoses. We evaluated a cohort of patients on long-term triazole therapy and found that other fluorinated triazoles (fluconazole and posaconazole) conferred no risk for the development of hyperfluorosis and its complications in our cohort.
摘要
使用三氟嘧啶类抗真菌药伏立康唑与氟过量和骨膜炎/外生骨疣的发生有关。我们评估了长期接受三唑类药物治疗的患者队列，发现其他氟代三唑类药物（氟康唑和泊沙康唑）在我们的队列中不会增加氟中毒及其并发症的发生风险。
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本文引用的文献
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2
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