伊曲康唑治疗球孢子菌病慢性期。
Isavuconazole in the Treatment of Chronic Forms of Coccidioidomycosis.
机构信息
Department of Medicine, Division of Infectious Diseases, Kern Medical Center-University of California-Los Angeles, Bakersfield, California, USA.
Valley Fever Institute, Bakersfield, California, USA.
出版信息
Clin Infect Dis. 2023 Jun 16;76(12):2196-2199. doi: 10.1093/cid/ciad146.
Abstract
Coccidioidomycosis is a fungal infection with a range of clinical manifestations. Currently used antifungal agents exhibit variable efficacy and toxicity profiles that necessitate evaluation of additional therapeutic options. Improvement was observed in the majority of patients treated with isavuconazole, with clinical failures observed only in those with coccidioidal meningitis.
摘要
球孢子菌病是一种具有多种临床表现的真菌感染。目前使用的抗真菌药物表现出不同的疗效和毒性特征，这需要评估更多的治疗选择。伊曲康唑治疗的大多数患者都有改善，只有患有球孢子菌性脑膜炎的患者才观察到临床失败。
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