Krzyżaniak Alicja, Kaczmarek Maria, Stawińska-Witoszyńska Barbara, Krzywińska-Wiewiorowska Małgorzata
Department of Epidemiology, Karol Marcinkowski University of Medical Science, Poznań, Poland.
Med Wieku Rozwoj. 2011 Jul-Sep;15(3):282-7.
The aim of the study was to assess the prevalence of elevated blood pressure values and significant family history with respect to the incidence of cardiovascular diseases in overweight and obese adolescents.
Our study encompassed 4904 adolescents from randomly selected schools from the Wielkopolska province of Poland. Measurements of body height and mass were performed in all the school pupils. The adolescents were qualified to be included in the overweight and obese groups based on the BMI value, using the cut-off points according to Cole's method. Blood pressure measurements were conducted according to the methodology and recommendations of the Fourth Report, with the application of the Polish blood pressure standards. Within the group of students with normal body mass, overweight and obesity, the frequency of higher systolic and diastolic blood pressure and significant family history were calculated, and the relationship between the variables was calculated by means of chi2 test, assuming p<0.05. In order to calculate the odds ratio and the probability of incidence of higher systolic and diastolic blood pressure, the variables significant in the logistic regression model were taken into consideration.
Overweight and obesity was observed in 845 subjects, which made up 17.2% of the population included in the study. Overweight and obesity were significantly more often observed in boys (485 - 22,2%) than in girls (362 - 17.0%) (p<0.05). In boys, the significant family history increases the odds ratio of prevalence of higher systolic blood pressure 1.90 times, obesity - 8.86 times and significant family history combined with obesity - 16.85 times, in comparison with the boys who have normal body mass and no significant family history. Obesity in girls increases the odds ratio of prevalence of higher systolic blood pressure by 9.24 times. Obesity in boys increases the odds ratio of prevalence of higher diastolic blood pressure by 5.88 and in obese girls the odds ratio of elevated diastolic blood pressure are 4.17 times higher.
本研究旨在评估超重和肥胖青少年中血压值升高及显著家族病史与心血管疾病发病率之间的关系。
我们的研究涵盖了来自波兰大波兰省随机选取学校的4904名青少年。对所有在校学生进行了身高和体重测量。根据科尔方法的切点,依据BMI值将青少年纳入超重和肥胖组。按照第四次报告的方法和建议,采用波兰血压标准进行血压测量。在体重正常、超重和肥胖的学生群体中,计算收缩压和舒张压升高以及显著家族病史的频率,并通过卡方检验计算变量之间的关系,假设p<0.05。为了计算比值比以及收缩压和舒张压升高的发病概率,考虑了逻辑回归模型中有显著意义的变量。
845名受试者存在超重和肥胖,占研究总人群的17.2%。超重和肥胖在男孩中(485名,占22.2%)的发生率显著高于女孩(362名,占17.0%)(p<0.05)。与体重正常且无显著家族病史的男孩相比,男孩中的显著家族病史使收缩压升高患病率的比值比增加1.90倍,肥胖增加8.86倍,显著家族病史合并肥胖增加16.85倍。女孩肥胖使收缩压升高患病率的比值比增加9.24倍。男孩肥胖使舒张压升高患病率的比值比增加5.88倍,肥胖女孩舒张压升高的比值比高4.17倍。