Neurocenter of Southern Switzerland (EOC), Ospedale Civico, EOC Via Tesserete 46, 6900 Lugano, Switzerland.
Muscle Nerve. 2011 Nov;44(5):833-7. doi: 10.1002/mus.22165.
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) affects various components and segments of the peripheral nervous system differently, and thus there can be phenotypic heterogeneity. We report a 47-year-old woman with chronic sensory disturbances and proximal weakness limited to the legs. Motor and sensory nerve conduction studies were normal. Somatosensory evoked potentials and imaging indicated a demyelinating process involving the lumbosacral roots. The patient responded favorably to IVIg. Although she did not fulfill the diagnostic criteria for CIDP we believe this patient represents a restricted regional CIDP variant.
慢性炎症性脱髓鞘性多发性神经病（CIDP）会影响外周神经系统的不同部位和组分，因此可能存在表型异质性。我们报告了一例 47 岁女性，主要表现为慢性感觉障碍和下肢近端无力。运动和感觉神经传导研究正常。体感诱发电位和影像学提示存在累及腰骶神经根的脱髓鞘过程。患者对 IVIg 治疗反应良好。尽管该患者不符合 CIDP 的诊断标准，但我们认为这代表了一种局限型区域性 CIDP 变异型。
