United BioSource Corporation, Outcomes Research, Bethesda, MD, USA.
J Dermatolog Treat. 2013 Feb;24(1):50-9. doi: 10.3109/09546634.2011.631980. Epub 2011 Nov 10.
The patient-reported Dermatology Life Quality Index (DLQI) measures the impact of dermatologic diseases on patients' lives.
To evaluate the content validity of the DLQI in patients with moderate to severe plaque psoriasis.
In a two-part interview, participants were first asked open-ended questions about the impact of psoriasis-related complaints and symptoms on their lives and activities. The DLQI was then administered and cognitive debriefing interviews assessed participants' understanding of the instructions, items, and response scales, and relevance of the specific items to their experience with psoriasis.
Twenty-one patients were interviewed at two US sites. Mean age was 48.8 years, 67% were white, and 43% reported Hispanic/Latino ethnicity. The majority reported living with a partner or spouse (81%) and working full time or part time (57%). Patients' spontaneous responses to open-ended questions were consistent with DLQI concepts and generally did not provide additional concepts. Most participants reported that the instructions, item content, and response scales were clear and easy to understand and relevant.
The content of the DLQI included all important and relevant concepts from the perspective of patients with moderate to severe plaque psoriasis. This study provides further support for the content validity of the DLQI in this population.
患者报告的皮肤病生活质量指数（DLQI）衡量皮肤病对患者生活的影响。
评估 DLQI 在中重度斑块型银屑病患者中的内容效度。
在两部分访谈中，首先让参与者回答有关银屑病相关投诉和症状对其生活和活动影响的开放式问题。然后，进行 DLQI 测试，并进行认知性访谈，评估参与者对说明、项目和反应量表的理解，以及特定项目与他们银屑病经历的相关性。
在美国的两个地点对 21 名患者进行了访谈。平均年龄为 48.8 岁，67%为白人，43%报告为西班牙裔/拉丁裔。大多数患者报告与伴侣或配偶一起生活（81%），全职或兼职工作（57%）。患者对开放式问题的自发反应与 DLQI 概念一致，通常没有提供其他概念。大多数参与者表示，说明、项目内容和反应量表清晰易懂且相关。
从中重度斑块型银屑病患者的角度来看，DLQI 包含了所有重要和相关的概念。本研究进一步支持了该人群中 DLQI 的内容效度。
