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2
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本文引用的文献

1
Genetics of kidney failure and the evolving story of APOL1.肾衰竭的遗传学及 APOL1 的演进故事。
J Clin Invest. 2011 Sep;121(9):3367-74. doi: 10.1172/JCI46263. Epub 2011 Sep 1.
2
Albuminuria and racial disparities in the risk for ESRD.蛋白尿与终末期肾病风险的种族差异。
J Am Soc Nephrol. 2011 Sep;22(9):1721-8. doi: 10.1681/ASN.2010101085. Epub 2011 Aug 25.
3
The APOL1 gene and allograft survival after kidney transplantation.APOL1 基因与肾移植后移植物的存活。
Am J Transplant. 2011 May;11(5):1025-30. doi: 10.1111/j.1600-6143.2011.03513.x. Epub 2011 Apr 12.
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Intensive blood-pressure control in hypertensive chronic kidney disease.高血压性慢性肾脏病的强化血压控制。
N Engl J Med. 2010 Sep 2;363(10):918-29. doi: 10.1056/NEJMoa0910975.
5
Association of trypanolytic ApoL1 variants with kidney disease in African Americans.载脂蛋白 L1 变体与非裔美国人肾脏疾病的关联。
Science. 2010 Aug 13;329(5993):841-5. doi: 10.1126/science.1193032. Epub 2010 Jul 15.
6
Essential hypertension and risk of nephropathy: a reappraisal.原发性高血压与肾病风险:再评价。
Curr Opin Nephrol Hypertens. 2010 May;19(3):235-41. doi: 10.1097/MNH.0b013e3283366344.
7
Ethnic differences in the relationship between albuminuria and calcified atherosclerotic plaque: the African American-diabetes heart study.白蛋白尿与钙化粥样硬化斑块之间关系的种族差异:非裔美国人-糖尿病心脏研究。
Diabetes Care. 2010 Jan;33(1):131-8. doi: 10.2337/dc09-1253. Epub 2009 Oct 13.
8
Prognostic value of serum creatinine and effect of treatment of hypertension on renal function. Results from the hypertension detection and follow-up program. The Hypertension Detection and Follow-up Program Cooperative Group.血清肌酐的预后价值及高血压治疗对肾功能的影响。高血压检测与随访项目的结果。高血压检测与随访项目合作组
Hypertension. 1989 May;13(5 Suppl):I80-93. doi: 10.1161/01.hyp.13.5_suppl.i80.
9
Renal function change in hypertensive members of the Multiple Risk Factor Intervention Trial. Racial and treatment effects. The MRFIT Research Group.多重危险因素干预试验中高血压患者的肾功能变化。种族及治疗效果。MRFIT研究小组。
JAMA. 1992 Dec 2;268(21):3085-91.

危险因素:种族、肾脏疾病和蛋白尿。

Risk factors: Race, renal disease and albuminuria.

出版信息

Nat Rev Nephrol. 2011 Oct 18;7(12):679-80. doi: 10.1038/nrneph.2011.154.

DOI:10.1038/nrneph.2011.154
PMID:22009246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3280425/
Abstract

A new report suggests that differences in albuminuria might contribute to disparities in susceptibility to nephropathy in African American and white individuals. Interpretation of this finding requires consideration of renal histology, clinical trials and genetic studies. These factors indicate that a far more complex scenario is likely to exist than previously thought.

摘要

一份新报告表明,白蛋白尿的差异可能导致非裔美国人和白人个体对肾病易感性的差异。对这一发现的解释需要考虑肾脏组织学、临床试验和遗传研究。这些因素表明,可能存在比以前想象的更为复杂的情况。