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本文引用的文献

1
The apolipoprotein L1 (APOL1) gene and nondiabetic nephropathy in African Americans.载脂蛋白 L1(APOL1)基因与非糖尿病性非洲裔美国人肾病。
J Am Soc Nephrol. 2010 Sep;21(9):1422-6. doi: 10.1681/ASN.2010070730. Epub 2010 Aug 5.
2
Association of trypanolytic ApoL1 variants with kidney disease in African Americans.载脂蛋白 L1 变体与非裔美国人肾脏疾病的关联。
Science. 2010 Aug 13;329(5993):841-5. doi: 10.1126/science.1193032. Epub 2010 Jul 15.
3
Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene.APOL1 基因中的错义突变与之前归因于 MYH9 基因的终末期肾病风险高度相关。
Hum Genet. 2010 Sep;128(3):345-50. doi: 10.1007/s00439-010-0861-0. Epub 2010 Jul 16.
4
Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis.估算肾小球滤过率和白蛋白尿与普通人群全因和心血管死亡率的关系:荟萃分析协作研究。
Lancet. 2010 Jun 12;375(9731):2073-81. doi: 10.1016/S0140-6736(10)60674-5. Epub 2010 May 17.
5
Differences in albuminuria between Hispanics and whites: an evaluation by genetic ancestry and country of origin: the multi-ethnic study of atherosclerosis.西班牙裔与白人之间蛋白尿的差异:基于遗传血统和原籍国的评估:动脉粥样硬化的多民族研究
Circ Cardiovasc Genet. 2010 Jun;3(3):240-7. doi: 10.1161/CIRCGENETICS.109.914499. Epub 2010 May 5.
6
Racial/ethnic differences in microalbuminuria among adults with prehypertension and hypertension: National Health and Nutrition Examination Survey (NHANES), 1999-2006.成年人高血压前期和高血压患者中微量白蛋白尿的种族/民族差异:1999-2006 年全国健康和营养调查(NHANES)。
Am J Hypertens. 2010 Aug;23(8):859-64. doi: 10.1038/ajh.2010.77. Epub 2010 Apr 22.
7
The spectrum of MYH9-associated nephropathy.MYH9 相关肾病的谱。
Clin J Am Soc Nephrol. 2010 Jun;5(6):1107-13. doi: 10.2215/CJN.08721209. Epub 2010 Mar 18.
8
Genetic ancestry is associated with subclinical cardiovascular disease in African-Americans and Hispanics from the multi-ethnic study of atherosclerosis.在动脉粥样硬化多族裔研究中,遗传血统与非裔美国人和西班牙裔人群的亚临床心血管疾病相关。
Circ Cardiovasc Genet. 2009 Dec;2(6):629-36. doi: 10.1161/CIRCGENETICS.109.876243. Epub 2009 Sep 19.
9
Ethnic differences in the relationship between albuminuria and calcified atherosclerotic plaque: the African American-diabetes heart study.白蛋白尿与钙化粥样硬化斑块之间关系的种族差异:非裔美国人-糖尿病心脏研究。
Diabetes Care. 2010 Jan;33(1):131-8. doi: 10.2337/dc09-1253. Epub 2009 Oct 13.
10
Blood pressure, atherosclerosis, and albuminuria in 10,113 participants in the atherosclerosis risk in communities study.社区动脉粥样硬化风险研究中10113名参与者的血压、动脉粥样硬化和蛋白尿情况。
J Hypertens. 2009 Feb;27(2):397-409. doi: 10.1097/hjh.0b013e32831aede6.

种族对蛋白尿以及心血管和肾脏疾病风险的影响。

Effects of race on albuminuria and risk of cardiovascular and kidney disease.

作者信息

Buckalew Vardaman M, Freedman Barry I

机构信息

Department of Internal Medicine, Section on Nephrology, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1053, USA.

出版信息

Expert Rev Cardiovasc Ther. 2011 Feb;9(2):245-9. doi: 10.1586/erc.10.185.

DOI:10.1586/erc.10.185
PMID:21453219
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3171951/
Abstract

The literature describing the relationship between urinary protein excretion and risk of cardiovascular disease and renal disease is rapidly proliferating. Several studies have demonstrated racial differences in the relationship between albuminuria and associated disorders. The purpose of this article is to summarize the effects of race on the relationship between albuminuria and renal and cardiovascular disease risk, propose explanatory hypotheses, and suggest directions for future investigation.

摘要

描述尿蛋白排泄与心血管疾病和肾脏疾病风险之间关系的文献正在迅速增加。几项研究已经证明了蛋白尿与相关疾病之间关系存在种族差异。本文的目的是总结种族对蛋白尿与肾脏及心血管疾病风险之间关系的影响,提出解释性假设,并为未来的研究指明方向。