皮肤和皮下组织在杜普伊特伦挛缩中的作用：电子显微镜观察。
The role of skin and subcutaneous tissues in Dupuytren's contracture: an electron microscopic observation.
机构信息
Department of Orthopaedics, Second Affiliated Hospital, Medical College, Zhejiang University, Hangzhou, China.
出版信息
Orthop Surg. 2009 Aug;1(3):216-21. doi: 10.1111/j.1757-7861.2009.00028.x.
OBJECTIVE
To determine the relationship between the overlying tissues and recurrence of Dupuytren's contracture.
METHODS
Forty-three patients (68 hands) who accepted surgical treatment were divided into two groups according to treatment methods: partial fasciectomy or dermofasciectomy and full-thickness skin graft. Diseased palmar fascia, subcutaneous tissues and skin obtained during surgery were then assessed by electron microscopy.
RESULTS
All patients were followed up. None of the hands which accepted dermofasciectomy and full-thickness skin grafting recurred, while 46.4% of the hands which accepted partial fasciectomy recurred. Under electron microscopic observation, myofibroblasts were found in the skin and subcutaneous tissues.
CONCLUSION
The overlying tissues play an important role in Dupuytren's contracture, which may be a reason for recurrence of this condition after surgical treatment.
目的
探讨掌腱膜挛缩症复发与覆盖组织的关系。
方法
43 例（68 只手）患者根据手术方法分为两组：部分筋膜切除术或皮下松解术联合全厚皮片移植术，对术中获取的病变掌腱膜、皮下组织和皮肤进行电镜观察。
结果
所有患者均获随访，接受皮下松解术联合全厚皮片移植术的手均未复发，接受部分筋膜切除术的手复发率为 46.4%。电镜下发现皮肤和皮下组织中有肌成纤维细胞。
结论
覆盖组织在掌腱膜挛缩症中起重要作用，这可能是术后该疾病复发的原因之一。
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