Madhu S K, Vijayan V A
Vector Biology Research Lab, Department of Studies in Zoology, University of Mysore, Manasagangotri, Mysore-570 006, Karnataka, India.
J Commun Dis. 2009 Sep;41(3):169-74.
Insect growth regulator (IGR), pyriproxyfen is a juvenile hormone analogue used in stored product insect pest and vector control programmes. It can be considered as an alternative source to conventional insecticides because of its specific activity against immature insects, low persistence in the environment and virtually nontoxic to mammals. So, in our laboratory the effect of Pyriproxyfen was evaluated against the late 3rd instar larvae of Culex quinquefasciatus and Aedes aegypti to study the Concentration-mortality response and inhibition of adult emergence. The results showed that LC50 was 0.00084 ppm and 0.00166 ppm for Cx. quinquefasciatus and A. aegypti respectively. Toxicity of this insect compound extended till the adult emergence by inhibiting pupae formation up to 61.0% and 95.6% of adult emergence against Cx. quinquefasciatus. Likewise it affected 65.0% of pupal formation and 98.9% of adult emergence against A. aegypti. These results represent a promising strategy to use insect growth regulator, Pyriproxyfen for the instant, safe and successful improvement in the integrated vector control programme.
昆虫生长调节剂（IGR）吡丙醚是一种用于仓储害虫和病媒控制项目的保幼激素类似物。由于其对未成熟昆虫具有特定活性、在环境中持久性低且对哺乳动物几乎无毒，它可被视为传统杀虫剂的替代来源。因此，在我们实验室中，评估了吡丙醚对致倦库蚊和埃及伊蚊末龄3龄幼虫的作用，以研究浓度-死亡率反应以及对成虫羽化的抑制作用。结果表明，致倦库蚊和埃及伊蚊的LC50分别为0.00084 ppm和0.00166 ppm。这种昆虫化合物的毒性一直持续到成虫羽化，对致倦库蚊抑制蛹形成达61.0%，抑制成虫羽化达95.6%。同样，对埃及伊蚊，它影响65.0%的蛹形成和98.9%的成虫羽化。这些结果代表了一种有前景的策略，即使用昆虫生长调节剂吡丙醚来即时、安全且成功地改进综合病媒控制项目。
