Laboratory evaluation of a juvenile hormone mimic, pyriproxyfen on Culex quinquefasciatus Say and Aedes aegypti Linn. at Mysore, India.

Insect growth regulator (IGR), pyriproxyfen is a juvenile hormone analogue used in stored product insect pest and vector control programmes. It can be considered as an alternative source to conventional insecticides because of its specific activity against immature insects, low persistence in the environment and virtually nontoxic to mammals. So, in our laboratory the effect of Pyriproxyfen was evaluated against the late 3rd instar larvae of Culex quinquefasciatus and Aedes aegypti to study the Concentration-mortality response and inhibition of adult emergence. The results showed that LC50 was 0.00084 ppm and 0.00166 ppm for Cx. quinquefasciatus and A. aegypti respectively. Toxicity of this insect compound extended till the adult emergence by inhibiting pupae formation up to 61.0% and 95.6% of adult emergence against Cx. quinquefasciatus. Likewise it affected 65.0% of pupal formation and 98.9% of adult emergence against A. aegypti. These results represent a promising strategy to use insect growth regulator, Pyriproxyfen for the instant, safe and successful improvement in the integrated vector control programme.