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应用机械植入技术评估间质环角膜段治疗 LASIK 后扩张患者。

Evaluation of intrastromal corneal ring segments for treatment of post-LASIK ectasia patients with a mechanical implantation technique.

机构信息

Department of Ophthalmology, Maltepe University School of Medicine, Istanbul, Turkey.

出版信息

Indian J Ophthalmol. 2011 Nov-Dec;59(6):437-43. doi: 10.4103/0301-4738.86310.

DOI:10.4103/0301-4738.86310
PMID:22011487
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3214413/
Abstract

AIM

To evaluate the clinical outcomes of Keraring segment implantation in patients with post- laser-assisted in situ keratomileusis (LASIK) ectasia, using a mechanical implantation technique.

MATERIALS AND METHODS

Twelve eyes of 10 patients with post-LASIK ectasia were enrolled. Intracorneal ring segments (ICRS) were implanted after dissection of the tunnel using Tunc's specially designed dissector under suction. A complete ophthalmic examination was performed, including uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), spherical equivalent, keratometric (K) readings, inferosuperior asymmetry index (ISAI), and ultrasound pachymetry. All 3, 6, and 12-month follow-ups were completed, and statistical analysis was performed.

RESULTS

The mean preoperative UDVA for all eyes was 1.28 ± 0.59 logMAR. At 12 months, the mean UDVA was 0.36 ± 0.19 logarithm of the Minimum Angle of Resolution (logMAR) (P=0.002), and the mean preoperative CDVA was 0.58 ± 0.3 logMAR, which improved to 0.15 ± 0.12 (P=0.002) at 1 year. There was a significant reduction in cylindrical refractive and spherical equivalent refractive error from -5.29 ± 2.47 diopters (D) and -5.54 ± 5.04 D preoperatively to -1.47 ± 0.71 D and -0.74 ± 1.07 D (P=0.001, P=0.002), respectively, at 1 year. In the same period, the mean K- readings improved from 47.93 ± 4.84 D to 40.87 ± 2.36 D (P=0.002), and the mean ISAI improved from 5.34 ± 3.05 to 2.37 ± 1.68 (P=0.003). No significant changes in mean central corneal thickness were observed postoperatively. There were no major complications during or after surgery.

CONCLUSION

ICRS implantation using a unique mechanical dissection technique is a safe and effective treatment for post-LASIK ectasia. All parameters showed improvement at 1-year follow-up.

摘要

目的

采用机械植入技术,评估 Keraring 段植入治疗 LASIK 后扩张患者的临床疗效。

材料与方法

纳入 10 例(12 只眼)LASIK 后扩张患者。使用 Tunc 专门设计的带吸引器的分离器在隧道内进行解剖后,植入眼内环段(ICRS)。进行全面的眼科检查,包括未矫正远视力(UDVA)、矫正远视力(CDVA)、等效球镜、角膜曲率(K)读数、下上不对称指数(ISAI)和超声角膜测厚。所有患者均完成 3、6 和 12 个月的随访,并进行统计学分析。

结果

所有患者术前平均 UDVA 为 1.28 ± 0.59 对数最小分辨角(logMAR)。术后 12 个月,平均 UDVA 为 0.36 ± 0.19 对数最小分辨角(logMAR)(P=0.002),术前平均 CDVA 为 0.58 ± 0.3 logMAR,术后 1 年提高至 0.15 ± 0.12(P=0.002)。术后 1 年,等效球镜和柱镜屈光度从术前的-5.29 ± 2.47 屈光度(D)和-5.54 ± 5.04 D 显著降低至-1.47 ± 0.71 D 和-0.74 ± 1.07 D(P=0.001,P=0.002)。同期,平均 K 值从 47.93 ± 4.84 D 提高至 40.87 ± 2.36 D(P=0.002),平均 ISAI 从 5.34 ± 3.05 提高至 2.37 ± 1.68(P=0.003)。术后中央角膜厚度无明显变化。术中及术后无严重并发症发生。

结论

采用独特的机械分离技术植入 ICRS 是治疗 LASIK 后扩张的一种安全有效的方法。所有参数在 1 年随访时均得到改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ec2/3214413/5435c875dcfd/IJO-59-437-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ec2/3214413/b5ff7fa0f90a/IJO-59-437-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ec2/3214413/4c2c19f37035/IJO-59-437-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ec2/3214413/0fd7be9e04af/IJO-59-437-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ec2/3214413/f26df037cf9d/IJO-59-437-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ec2/3214413/ae46d3016554/IJO-59-437-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ec2/3214413/5435c875dcfd/IJO-59-437-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ec2/3214413/b5ff7fa0f90a/IJO-59-437-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ec2/3214413/4c2c19f37035/IJO-59-437-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ec2/3214413/0fd7be9e04af/IJO-59-437-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ec2/3214413/f26df037cf9d/IJO-59-437-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ec2/3214413/ae46d3016554/IJO-59-437-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ec2/3214413/5435c875dcfd/IJO-59-437-g008.jpg

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