Multidrug-Resistant Organism Repository and Surveillance Network, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, USA.
Infect Control Hosp Epidemiol. 2011 Nov;32(11):1116-9. doi: 10.1086/662380. Epub 2011 Sep 20.
We describe the clinical, microbiologic, and molecular features of the first series of qacA/B-containing strains of methicillin-resistant Staphylococcus aureus from infected US patients. All qac-carrying strains were clonally diverse, and qacA strains exhibited increased tolerance to chlorhexidine as measured by minimum inhibitory concentrations, minimum bactericidal concentrations, and postexposure colony counts.
我们描述了来自美国感染患者的耐甲氧西林金黄色葡萄球菌中第一批含有 qacA/B 的菌株的临床、微生物学和分子特征。所有携带 qac 的菌株均具有不同的克隆多样性,并且 qacA 菌株表现出对氯己定的更高耐受性,这可以通过最小抑菌浓度、最小杀菌浓度和暴露后菌落计数来衡量。