耐酸性 L-阿拉伯糖异构酶的超分子稳定化来自清酒乳杆菌。
Supramolecular stabilization of acid tolerant L-arabinose isomerase from Lactobacillus sakei.
机构信息
LMI CNRS UMR 5615, Université de Lyon 1, Villeurbanne, F69622, France.
出版信息
Chem Commun (Camb). 2011 Dec 7;47(45):12307-9. doi: 10.1039/c1cc14930j. Epub 2011 Oct 20.
PMID:22012067
Abstract
L-Arabinose isomerase stability is a crucial criterion for the industrial application of this biocatalyst. Noria and NoriaPG are capable of increasing the L-arabinose isomerase stability not only at high temperatures but also at low pH. Such results highlight, for the first time, the use of the Noria series of molecules for protein stabilization and activation.
摘要
L-阿拉伯糖异构酶稳定性是该生物催化剂工业应用的关键标准。Noria 和 NoriaPG 不仅能够提高 L-阿拉伯糖异构酶在高温下的稳定性，还能够提高其在低 pH 值下的稳定性。这些结果首次强调了 Noria 系列分子在蛋白质稳定和激活方面的应用。
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