University of Rochester, Rochester, NY, USA.
Neurology. 2011 Nov 15;77(20):1808-11. doi: 10.1212/WNL.0b013e3182377e29. Epub 2011 Oct 19.
To determine if remote administration of the Unified Batten Disease Rating Scale (UBDRS) Physical Impairment subscale by telemedicine is reliable and feasible across a broad range of disease severity.
For the majority (n = 10) of subjects, the examination was performed by a nonphysician who had been trained to perform the examination but not to score the subjects. A trained rater scored the subjects via live video; a second trained rater performed a separate examination in person and scored that examination. For 3 telemedicine evaluations, examinations were performed and scored by a trained rater while a second trained rater simultaneously scored the subjects via live video. Reliability was determined by intraclass correlation coefficient (ICC).
Subjects (n = 13) represented a wide range of disease severity. Remote administration of the UBDRS Physical Impairment subscale had high interrater reliability across all subjects (ICC = 0.94). When only the subjects (n = 10) who had been examined by the nonphysician and scored remotely were included in the analysis, the reliability was unchanged (ICC = 0.95).
The UBDRS Physical Impairment subscale is reliable and feasible for remote administration. Telemedicine has the potential to be a useful tool in rare neurologic disease research and clinical assessment.
通过远程医疗确定广泛疾病严重程度范围内远程管理统一脑腱黄瘤病评定量表（UBDRS）身体损伤分量表是否可靠且可行。
对于大多数（n=10）受试者，由经过培训但不评分的非医师进行检查。经过培训的评分员通过实时视频对受试者进行评分；另一位经过培训的评分员亲自进行单独检查并对该检查进行评分。对于 3 次远程医疗评估，由经过培训的评分员进行检查和评分，同时第二位经过培训的评分员通过实时视频同时对受试者进行评分。可靠性通过组内相关系数（ICC）确定。
受试者（n=13）代表了广泛的疾病严重程度。UBDRS 身体损伤分量表的远程管理在所有受试者中均具有很高的评分者间可靠性（ICC=0.94）。当仅包括由非医师检查和远程评分的受试者（n=10）进行分析时，可靠性保持不变（ICC=0.95）。
UBDRS 身体损伤分量表可靠且适用于远程管理。远程医疗有可能成为罕见神经疾病研究和临床评估的有用工具。
