Proença R, Machado J, Maltez F, Alberto M J, Martins G, Gonçalves P
Hospital de Curry Cabral, Serviço 1.
Rev Port Cardiol. 1990 Apr;9(4):333-7.
We describe four cases of primary hyperaldosteronism whose initial presentation was a moderate to severe hypertension. In three patients an adrenal adenoma was found; in another patient was due to unilateral adrenal hyperplasia. A good therapeutic response was achieved in all cases by unilateral adrenalectomy. The captopril test (Lyons version) proved useful to exclude essential hypertension and, may be, in distinguishing the new sub-types of primary hyperaldosteronism recently described. Indeed, only in the case of unilateral adrenal hyperplasia a fall in plasma aldosterone levels was observed. However, we feel that further investigation is needed to clarify this point.
我们描述了4例原发性醛固酮增多症患者，其最初表现为中度至重度高血压。3例患者发现肾上腺腺瘤；另1例患者病因是单侧肾上腺增生。所有病例通过单侧肾上腺切除术均取得了良好的治疗效果。卡托普利试验（莱昂斯版本）被证明有助于排除原发性高血压，或许还有助于区分最近描述的原发性醛固酮增多症新亚型。事实上，仅在单侧肾上腺增生的病例中观察到血浆醛固酮水平下降。然而，我们认为需要进一步研究以阐明这一点。
