Institute for Research in Molecular Medicine (INFORMM), University Sains Malaysia, Pulau Pinang, Malaysia.
Eur Rev Med Pharmacol Sci. 2011 Sep;15(9):1027-33.
Hevea brasiliensis extract could potentially be employed as a relatively low cost resource for various anti-fungal activities due to the simplicity of latex preparation and the abundance of latex that can be obtained in rubber producing regions. The present study was aimed at examining the species specific anti-fungal property of H. brasilensis latex C-serum against Aspergillus niger.
The results showed that the latex C-serum exerted a specific antifungal activity against Aspergillus niger, but not Candida albicans. Low toxicity of the C-serum was demonstrated in Brine Shrimp Lethality Test (BSLT) with an LC50 value of 98.4 mg/ml.
Pending further more elaborated investigations, H. brasiliensis latex C-serum, with its species specific anti-fungal and cancer-origin cell line specific anti-proliferation properties, would probably contribute in healthcare in addition to its traditional role in polymer industry.
由于胶乳制备简单，且在橡胶生产地区可获得大量胶乳，巴西橡胶树提取物可能作为一种相对低成本的资源应用于各种抗真菌活性。本研究旨在检测巴西橡胶树乳胶 C 血清对黑曲霉的种特异性抗真菌特性。
结果表明，乳胶 C 血清对黑曲霉具有特异性抗真菌活性，但对白色念珠菌没有活性。在卤虫致死试验（BSLT）中，C 血清表现出低毒性，LC50 值为 98.4mg/ml。
在进一步更详细的研究之前，巴西橡胶树乳胶 C 血清具有种特异性抗真菌和癌细胞系特异性抗增殖特性，除了在聚合物工业中的传统作用外，可能会为医疗保健做出贡献。
