Interdisciplinary School of Health Sciences, University of Pune, Pune, India.
Int J Food Sci Nutr. 2012 May;63(3):343-52. doi: 10.3109/09637486.2011.627848. Epub 2011 Oct 21.
To evaluate the effect of galacto-fructo-oligosaccharide (G-FOS) fortification of non-dairy snack on relative calcium absorption, 61 girls (15-18 years) were randomly allocated to three equal groups; (i) Group-P, fermented-malted finger-millet pancake with soy coconut dip (snack; 534 mg calcium/serving); (ii) Group-G, snack fortified with G-FOS (8 g); (iii) Group-C: low calcium rice-flakes snack with calcium carbonate (540 mg). Group-G snack had lower pH (5.9) and higher total fatty acid content than group-P. After a 12-h fast, serum ionized calcium (iCa), intact parathyroid hormone (PTH) were measured at 0, 1, 3, 5, 7, 9 h after the ingestion of snack. Increment in area under the curve over baseline (ΔAUC) in iCa was higher in group-G(9.1%), as compared to group-P(1.4%) (p < 0.05) and group-C(3.1%). PTH ΔAUC was 39.7% higher for group-G as compared to group-P (p>0.1) but lower than group-C. In conclusion, calcium absorption is enhanced by G-FOS fortification and fermentation, which may be mediated through increased fatty acid content of the snack.
为了评估在非乳制品零食中添加半乳寡糖（G-FOS）对相对钙吸收的影响，将 61 名女孩（15-18 岁）随机分为三组：（i）组-P，发酵麦芽小米煎饼配大豆椰奶蘸料（零食；每份 534 毫克钙）；（ii）组-G，添加 G-FOS（8 克）的零食；（iii）组-C：低钙大米薄片零食加碳酸钙（540 毫克）。组-G 零食的 pH 值（5.9）较低，总脂肪酸含量高于组-P。禁食 12 小时后，在摄入零食后 0、1、3、5、7、9 小时测量血清离子钙（iCa）和完整甲状旁腺激素（PTH）。与组-P（1.4%）（p<0.05）和组-C（3.1%）相比，组-G（9.1%）的 iCa 曲线下面积增量（ΔAUC）更高。与组-P 相比，组-G 的 PTH ΔAUC 高 39.7%（p>0.1），但低于组-C。总之，钙吸收通过 G-FOS 强化和发酵得到增强，这可能是通过增加零食中的脂肪酸含量来介导的。
