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2008年法国与富马酸二甲酯相关的皮炎暴发的流行病学描述

Epidemiological description of an outbreak of dermatitis related to dimethylfumarate, France, 2008.

作者信息

Lefranc Agnès, Flesch Françoise, Cochet Amandine, Daoudi Jamel, Crinier Raphaël

机构信息

French Institute for Public Health Surveillance (InVS), 12 rue du Val d'Osne, Saint Maurice cédex, France.

出版信息

Arch Environ Occup Health. 2011;66(4):217-22. doi: 10.1080/19338244.2011.564228.

DOI:10.1080/19338244.2011.564228
PMID:22014194
Abstract

Following similar events in other European countries, some cases of dermatitis related to contact with China-imported furniture possibly treated with dimethyl(E)-butenedioate (dimethylfumarate [DMF]) were reported to the French institute for public health surveillance at the beginning of September 2008. An active multisource case collection was conducted in order to provide an epidemiological description of this outbreak. Results of this investigation show that, in France, mainly during the 4th quarter of 2008, a large number of people presented dermatological symptoms at least plausibly due to a contact with DMF-treated consumer products. The products involved were mostly shoes and sofa (94% of cases). This work offers an example of a multipartner investigation in the field of environmental health. It also shows how the results obtained contributed to decision-making and resulted in the limitation of DMF-treated products in France and in Europe.

摘要

继其他欧洲国家发生类似事件后,2008年9月初,法国公共卫生监测机构收到一些与接触从中国进口的、可能用(E)-丁烯二酸二甲酯(富马酸二甲酯[DMF])处理过的家具有关的皮炎病例报告。为了对此次疫情进行流行病学描述,开展了积极的多渠道病例收集工作。这项调查结果显示,在法国,主要是在2008年第四季度,大量民众出现了至少看似与接触经DMF处理的消费品有关的皮肤症状。所涉产品主要是鞋子和沙发(占病例的94%)。这项工作为环境卫生领域的多方合作调查提供了一个范例。它还展示了所获结果如何为决策提供依据,并导致法国和欧洲对经DMF处理的产品加以限制。

相似文献

1
Epidemiological description of an outbreak of dermatitis related to dimethylfumarate, France, 2008.2008年法国与富马酸二甲酯相关的皮炎暴发的流行病学描述
Arch Environ Occup Health. 2011;66(4):217-22. doi: 10.1080/19338244.2011.564228.
2
Correlation between lesion site and concentration of dimethyl fumarate in different parts of shoes in patients with contact dermatitis caused by dimethyl fumarate in footwear.接触性皮炎患者鞋内二甲基富马酸各部位皮损部位与二甲基富马酸浓度的相关性。
Contact Dermatitis. 2011 Aug;65(2):92-5. doi: 10.1111/j.1600-0536.2011.01922.x. Epub 2011 May 6.
3
An outbreak of furniture related dermatitis ('sofa dermatitis') in Finland and the UK: history and clinical cases.一起家具相关皮炎(“沙发皮炎”)在芬兰和英国的暴发:历史和临床病例。
J Eur Acad Dermatol Venereol. 2010 Apr;24(4):486-9. doi: 10.1111/j.1468-3083.2009.03429.x. Epub 2009 Sep 30.
4
Allergic contact dermatitis to shoes induced by dimethylfumarate: A new allergen imported from China.由富马酸二甲酯引起的鞋类过敏性接触性皮炎:一种从中国进口的新过敏原。
Dermatol Online J. 2010 Mar 15;16(3):3.
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Sofa dermatitis.沙发皮炎。
J Dtsch Dermatol Ges. 2010 Nov;8(11):897-9. doi: 10.1111/j.1610-0387.2010.07386.x.
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Shoe contact dermatitis from dimethyl fumarate: clinical manifestations, patch test results, chemical analysis, and source of exposure.富马酸二甲酯导致的接触性皮炎:临床表现、斑贴试验结果、化学分析和接触源。
Contact Dermatitis. 2009 Nov;61(5):249-60. doi: 10.1111/j.1600-0536.2009.01628.x.
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The cause of the Chinese sofa/chair dermatitis epidemic is likely to be contact allergy to dimethylfumarate, a novel potent contact sensitizer.中国沙发/座椅皮炎流行的原因可能是对富马酸二甲酯的接触性过敏,富马酸二甲酯是一种新型强效接触致敏剂。
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8
Dimethyl fumarate contact dermatitis of the foot: an increasingly widespread disease.二甲基富马酸引起的足部接触性皮炎:一种日益广泛传播的疾病。
Int J Dermatol. 2012 Jan;51(1):42-5. doi: 10.1111/j.1365-4632.2011.04916.x. Epub 2011 Sep 14.
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[Trichinellosis in Poland in 2010].[2010年波兰的旋毛虫病]
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Contact dermatitis to dimethylfumarate in armchairs.扶手椅中富马酸二甲酯引起的接触性皮炎
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