回顾性分析 39 例胸膜孤立性纤维瘤患者的临床资料并复习文献。
Retrospective analysis for thirty-nine patients with solitary fibrous tumor of pleura and review of the literature.
机构信息
Department of Thoracic Surgery, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Changjiang Route 10#, Chongqing, PR China.
出版信息
World J Surg Oncol. 2011 Oct 20;9:134. doi: 10.1186/1477-7819-9-134.
BACKGROUND
Solitary fibrous tumor of the pleura (SFTP) is an uncommon neoplasm arising from mesenchymal cells. The aim of this study is to summarize the experience and the outcome of the surgical treatment for 39 cases of SFTP.
METHODS
From January 2004 to December 2008, 39 patients underwent surgical resection of SFTP in our department. All patients had clinical follow-up by the same team of surgeons. The mean follow-up was 40.3 months.
RESULTS
A local removal of the neoplasm was accomplished by video-assisted thoracic surgery (VATS) in 9 patients (group A) and by thoracotomy in 30 patients (group B) respectively. Comparing with group B, operations in group A took significantly less operative time, blood loss and spent less time in the intensive care unit and hospital. All specimens were positive for CD34 and Bcl-2. One patient developed recurrence, and the remaining 38 patients are alive and disease free at the end of follow-up.
CONCLUSIONS
Malignant SFTP still had the potential recurrence. VATS represents the more acceptable choice for the selected patients with SFTP.
背景
胸膜孤立性纤维瘤（SFTP）是一种罕见的起源于间叶细胞的肿瘤。本研究旨在总结 39 例 SFTP 患者外科治疗的经验和结果。
方法
2004 年 1 月至 2008 年 12 月，我科对 39 例 SFTP 患者进行了外科切除术。所有患者均由同一组外科医生进行临床随访。平均随访时间为 40.3 个月。
结果
9 例患者（A 组）通过电视辅助胸腔镜手术（VATS）和 30 例患者（B 组）通过开胸手术分别完成了肿瘤的局部切除。与 B 组相比，A 组的手术时间、出血量、重症监护室和住院时间明显减少。所有标本均对 CD34 和 Bcl-2 呈阳性。1 例患者复发，其余 38 例患者在随访结束时均存活且无疾病。
结论
恶性 SFTP 仍有潜在的复发风险。VATS 是 SFTP 患者的更可接受的选择。
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