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源自武装部队病理研究所档案:胸膜局限性纤维瘤。

From the archives of the AFIP: Localized fibrous tumor of the pleura.

作者信息

Rosado-de-Christenson Melissa L, Abbott Gerald F, McAdams H Page, Franks Teri J, Galvin Jeffrey R

机构信息

Department of Radiology and Nuclear Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.

出版信息

Radiographics. 2003 May-Jun;23(3):759-83. doi: 10.1148/rg.233025165.

Abstract

Eighty-two localized fibrous tumors of the pleura (LFTP) were reviewed retrospectively for the clinical, pathologic, and radiologic findings. Forty-four women and 38 men ranged in age from 17 to 78 years (mean, 54.7 years). Sixty-four benign LFTP ranged in size from 2 to 30 cm (mean, 13.2 cm), and 18 malignant tumors ranged from 3 to 23 cm (mean, 14.4 cm). Forty-eight patients (60%) presented with symptoms. Radiographs of 76 patients demonstrated solitary masses occupying or extending into the inferior hemithorax (79%). Computed tomography (CT) of 78 lesions demonstrated lobular masses (83%) that formed at least one acute angle (96%) or only acute angles (65%) with the adjacent pleura. Heterogeneous lesion attenuation was documented in 88% of enhanced and in 68% of unenhanced CT scans. Contrast enhancement was common (62% of cases). Magnetic resonance (MR) imaging of 18 lesions demonstrated heterogeneous signal intensity on both T1- and T2-weighted images (78% and 83%, respectively). Multiplanar MR imaging allowed visualization of the diaphragm and documentation of an intrathoracic mass in all cases. LFTP are solitary lobular heterogeneous masses that occur in symptomatic adults and often affect the inferior hemithorax. Malignant lesions are radiologically indistinguishable from those with benign histologic characteristics. Radiographic and CT features characteristic of pleural location are typically absent.

摘要

对82例胸膜局限性纤维瘤(LFTP)进行回顾性分析,以观察其临床、病理及影像学表现。44例女性和38例男性,年龄范围为17至78岁(平均54.7岁)。64例良性LFTP大小为2至30 cm(平均13.2 cm),18例恶性肿瘤大小为3至23 cm(平均14.4 cm)。48例患者(60%)有症状。76例患者的X线片显示孤立性肿块占据或延伸至下胸部(79%)。78个病灶的计算机断层扫描(CT)显示小叶状肿块(83%),其与相邻胸膜形成至少一个锐角(96%)或仅为锐角(65%)。88%的增强CT扫描和68%的未增强CT扫描记录到病灶密度不均匀。强化常见(62%的病例)。18个病灶的磁共振(MR)成像在T1加权和T2加权图像上均显示信号强度不均匀(分别为78%和83%)。多平面MR成像在所有病例中均能显示膈肌并记录胸腔内肿块。LFTP是有症状成人中出现的孤立性小叶状不均匀肿块,常累及下胸部。恶性病变在影像学上与具有良性组织学特征的病变无法区分。通常缺乏胸膜定位的典型影像学和CT特征。

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