Cell Biology, University of Kaiserslautern, Erwin-Schrödinger-Strasse 13, 67663 Kaiserslautern, Germany.
Dev Cell. 2011 Oct 18;21(4):599-600. doi: 10.1016/j.devcel.2011.09.013.
Cristae junctions mark the boundaries of respiratory compartments in the inner mitochondrial membrane. In this issue of Developmental Cell, von der Malsburg et al. (2011) identify a complex, MINOS, that organizes cristae junctions. Mitofilin/Fcj1, the central component of the MINOS complex, also connects the inner membrane to outer membrane protein import machinery.
嵴连接标记了线粒体内膜呼吸区的边界。在本期《发育细胞》中,von der Malsburg 等人(2011)鉴定出一个复杂的 MINOS 复合物,该复合物组织嵴连接。MINOS 复合物的核心成分肌联蛋白/Fcj1 也将内膜与外膜蛋白导入机制连接起来。