Department of Medical Education, Gundersen Lutheran Medical Foundation, La Crosse, WI, USA.
Am J Surg. 2011 Dec;202(6):759-63; discussion 763-4. doi: 10.1016/j.amjsurg.2011.06.039. Epub 2011 Oct 19.
Portomesenteric venous thrombosis (PMVT) is uncommon but associated with ischemic bowel and mortality.
The purpose of this study was to determine the occurrence of PMVT in a community setting and evaluate current diagnosis, treatment, and outcomes.
Medical records of consecutive patients admitted to a community-based hospital diagnosed with PMVT were reviewed. Patients were divided into 2 groups: those diagnosed from 1997 to 2003 and those diagnosed from 2004 to 2009.
One hundred three patients were included. The proportion of chronic PMVT diagnoses increased in the recent group (14% in contrast to 44%, P = .001). Treatment was more common in acute in contrast to chronic PMVTs (70% in contrast to 48%, P = .035). The median length of stay decreased over time (6 in contrast to 3 days, P = .004). Three patients underwent surgical intervention. Overall, 30-day mortality was 17% and did not change over time.
Diagnosis and treatment have changed with increased differentiation between acute and chronic PMVT; outcomes were similar. Surgical intervention was rarely necessary. Mortality is attributed to patient comorbidity rather than PMVT.
门静脉肠系膜静脉血栓形成(PMVT)并不常见,但与缺血性肠病和死亡率相关。
本研究旨在确定社区环境中 PMVT 的发生情况,并评估当前的诊断、治疗和结果。
回顾性分析连续收治于社区医院的 PMVT 患者的病历。患者分为两组:1997 年至 2003 年诊断组和 2004 年至 2009 年诊断组。
共纳入 103 例患者。慢性 PMVT 诊断的比例在近期组中增加(14%对比44%,P=0.001)。急性 PMVT 治疗更为常见(70%对比48%,P=0.035)。住院时间随时间推移而缩短(6 天对比 3 天,P=0.004)。3 例患者接受了手术干预。总体而言,30 天死亡率为 17%,且随时间推移无变化。
随着对急性和慢性 PMVT 的区分增加,诊断和治疗发生了变化;结果相似。很少需要手术干预。死亡率归因于患者的合并症而非 PMVT。