Clinics of Pediatrics, Dr. Behcet Uz Children's Teaching and Research Hospital, 35210 Izmir, Turkey.
Gen Hosp Psychiatry. 2012 Jan-Feb;34(1):103.e5-6. doi: 10.1016/j.genhosppsych.2011.09.003. Epub 2011 Oct 19.
Steroid-induced psychosis is one of the most serious adverse effects of steroid therapy but is a little-known complication in children. There is no clear mechanism model for steroid-induced behavioral disturbance, but it may be related with dose or level of free fraction of steroids. Our case is a 12-year-old boy diagnosed with steroid-induced psychosis and treated with risperidone, an atypical antipsychotic, due to distinct psychotic symptoms. Pediatricians should be aware of this rare complication when administering corticosteroids for various medical illnesses.
类固醇诱导的精神病是类固醇治疗最严重的不良反应之一，但在儿童中却是一种鲜为人知的并发症。目前类固醇诱导行为障碍的机制模型尚不清楚，但可能与类固醇的剂量或游离分数水平有关。我们的病例是一名 12 岁男孩，因明显的精神病症状而被诊断为类固醇诱导的精神病，并接受了非典型抗精神病药物利培酮治疗。儿科医生在为各种疾病使用皮质类固醇时应该意识到这种罕见的并发症。
