Ferreira Daniela Cristina, Porto-Foresti Fabio, Oliveira Claudio, Foresti Fausto
Departamento de Morfologia; Instituto de Biociência; Universidade Estadual Paulista; Bauru, SP Brazil.
Mob Genet Elements. 2011 Jul;1(2):112-117. doi: 10.4161/mge.1.2.16731. Epub 2011 Jul 1.
Transposable elements are repetitive sequences with the capacity tomove inside of the genome. They constitute the majority of the eukaryotic genomes, and are extensively present in the human genome, representing more than 45% of the genome sequences. The knowledge of the origin and function of these elements in the fish genome is still reduced and fragmented, mainly with regard to its structure and organization in the chromosomes of the representatives of this biological group, with data currently available for very few species that represent the great variety of forms and existing diversity. Comparative analyses ascertain differences in the organization of such elements in the species studied up to the present. They can be part of the heterochromatic regions in some species or be spread throughout the genome in others. The main objective of the present revision is to discuss the aspects of the organization of transposable elements in the fish genome.
转座元件是具有在基因组内移动能力的重复序列。它们构成了真核生物基因组的大部分,并广泛存在于人类基因组中,占基因组序列的45%以上。关于这些元件在鱼类基因组中的起源和功能的知识仍然有限且零散,主要涉及它们在该生物类群代表物种染色体中的结构和组织,目前只有极少数代表了丰富多样形态和现存多样性的物种有相关数据。比较分析确定了到目前为止所研究物种中转座元件组织方式的差异。在一些物种中,它们可能是异染色质区域的一部分,而在其他物种中则可能遍布整个基因组。本次综述的主要目的是讨论鱼类基因组中转座元件的组织方面。