双胎妊娠妇女产后高血压的危险因素。

Risk factors for postpartum hypertension in women with twin pregnancies.

机构信息

Department of Obstetrics, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

出版信息

J Perinat Med. 2011 Oct 24;40(2):115-20. doi: 10.1515/JPM.2011.113.

DOI:10.1515/JPM.2011.113

PMID:22017329

Abstract

OBJECTIVE

Which physical findings and blood parameters predict postpartum hypertension remain to be studied in women with twin pregnancies.

METHODS

The antenatal systolic and diastolic blood pressures (SBP and DBP, respectively), and 16 laboratory variables were investigated in 150 normotensive women who gave birth to twins.

RESULTS

When the median values of the 18 continuous variables were used as cut-off values, an SBP>120 mm Hg (relative risk [95% confidence interval], 2.81 [1.94-4.08]), a DBP>70 mm Hg (2.42 [1.68-3.49]), an aspartate aminotransferase level>18 U/L (2.22 [1.55-3.19]), and a uric acid level>5.3 mg/dL (1.68 [1.20-2.36]) were independent risk factors for postpartum hypertension.

CONCLUSIONS

Antenatal blood pressure measurements and a laboratory work-up may be useful clinically for predicting postpartum hypertension in women with twin pregnancies.

摘要

目的

在双胎妊娠妇女中，哪些体格检查发现和血液参数可预测产后高血压仍有待研究。

方法

对 150 例血压正常的双胎分娩妇女进行了产前收缩压和舒张压（分别为 SBP 和 DBP）和 16 项实验室变量的调查。

结果

当 18 项连续变量的中位数用作截断值时，SBP>120mmHg（相对风险[95%置信区间]，2.81[1.94-4.08]）、DBP>70mmHg（2.42[1.68-3.49]）、天门冬氨酸氨基转移酶水平>18U/L（2.22[1.55-3.19]）和尿酸水平>5.3mg/dL（1.68[1.20-2.36]）是产后高血压的独立危险因素。