对妊娠糖尿病孕妇早期血糖检测中游离胰岛素DNA水平作为产后高血压预测指标的系统评价。
Systematic evaluation of cell-free insulin DNA levels in early blood glucose testing as a predictor of postpartum hypertension in pregnant women with gestational diabetes mellitus.
作者信息
Zhang Yuanyuan, Li Chunhua, Lin Rui, Feng Yan, Zhang Fang, Zhang Guangxia
机构信息
Department of Obstetrics and Gynecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University Jinan 250021, Shandong, China.
Department of Surgery and Anesthesiology, Dongchangfu District Maternal and Child Health Care Hospital Liaocheng 252004, Shandong, China.
出版信息
Am J Transl Res. 2022 Jun 15;14(6):4042-4049. eCollection 2022.
OBJECTIVE
To investigate the perinatal outcome of postpartum hypertension in pregnant women with gestational diabetes (GDM).
METHODS
A total of 100 puerperae who gave birth in our hospital from March 2018 to January 2020 were retrospectively analyzed. Among them, 50 patients were puerperae with postpartum hypertension (experimental group), and 50 puerperae had normal postpartum blood pressure (control group). Before delivery, fasting, postprandial and bedtime blood glucose, glycosylated hemoglobin, and urine glucose were compared between the two groups.
RESULTS
Before delivery, the experimental group observed significantly higher fasting, postprandial, and bedtime blood glucose, glycosylated hemoglobin, and urine glucose than the control group (P<0.05). A notable decline in natural delivery rate was witnessed in the experimental group (P<0.05). The two groups presented no significant differences in neonatal outcomes, neonatal blood glucose and blood pressure, maternal blood pressure at 30 weeks and 34 weeks of pregnancy, and blood lipid levels during pregnancy (P>0.05).
CONCLUSION
Postpartum hypertension in pregnant women with GDM results in a low probability of natural birth and it has a slight impact on the fetus.
目的
探讨妊娠期糖尿病（GDM）孕妇产后高血压的围产期结局。
方法
回顾性分析2018年3月至2020年1月在我院分娩的100例产妇。其中，50例为产后高血压产妇（实验组），50例产后血压正常产妇（对照组）。比较两组分娩前空腹、餐后及睡前血糖、糖化血红蛋白和尿糖情况。
结果
分娩前，实验组空腹、餐后及睡前血糖、糖化血红蛋白和尿糖均显著高于对照组（P<0.05）。实验组自然分娩率显著下降（P<0.05）。两组在新生儿结局、新生儿血糖和血压、妊娠30周和34周时的产妇血压以及孕期血脂水平方面无显著差异（P>0.05）。
结论
GDM孕妇产后高血压导致自然分娩概率较低，且对胎儿影响较小。
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