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评价一种新的针对体位性睡眠呼吸暂停患者的简单治疗方法。

Evaluation of a new simple treatment for positional sleep apnoea patients.

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, St. Lucas Andreas Hospital, Amsterdam, the Netherlands.

出版信息

J Sleep Res. 2012 Jun;21(3):322-9. doi: 10.1111/j.1365-2869.2011.00974.x. Epub 2011 Oct 22.

DOI:10.1111/j.1365-2869.2011.00974.x
PMID:22017727
Abstract

Obstructive sleep apnoea syndrome is a common clinical problem. Positional sleep apnoea syndrome, defined as having a supine apnoea-hypopnoea index of twice or more compared to the apnoea-hypopnoea index in the other positions, occurs in 56% of obstructive sleep apnoea patients. A limited number of studies focus on decreasing the severity of sleep apnoea by influencing sleep position. In these studies an object was strapped to the back (tennis balls, squash balls, special vests), preventing patients from sleeping in the supine position. Frequently, this was not successful due to arousals while turning from one lateral position to the other, thereby disturbing sleep architecture and sleep quality. We developed a new neck-worn device which influences sleep position by offering a vibration when in supine position, without significantly reducing total sleep time. Thirty patients with positional sleep apnoea were included in this study. No side effects were reported. The mean apnoea-hypopnoea index dropped from 27.7 ± 2.4 to 12.8 ± 2.2. Seven patients developed an overall apnoea-hypopnoea index below 5 when using the device in ON modus. We expect that positional therapy with such a device can be applied as a single treatment in many patients with mild to moderate position-dependent obstructive sleep apnoea, while in patients with a more severe obstructive sleep apnoea such a device could be used in combination with other treatment modalities.

摘要

阻塞性睡眠呼吸暂停综合征是一种常见的临床问题。体位性睡眠呼吸暂停综合征定义为仰卧位呼吸暂停-低通气指数是其他体位的两倍或以上,在阻塞性睡眠呼吸暂停患者中占 56%。少数研究关注通过影响睡眠姿势来降低睡眠呼吸暂停的严重程度。在这些研究中,将物体绑在背部(网球、壁球、特殊背心),防止患者仰卧。由于从一侧卧位转到另一侧时会被唤醒,因此经常无法成功,从而扰乱了睡眠结构和睡眠质量。我们开发了一种新的颈部佩戴装置,当患者处于仰卧位时会提供振动,从而影响睡眠姿势,而不会显著减少总睡眠时间。这项研究纳入了 30 名体位性睡眠呼吸暂停患者。没有报告任何副作用。平均呼吸暂停-低通气指数从 27.7±2.4 降至 12.8±2.2。在使用该装置的 ON 模式下,7 名患者的总呼吸暂停-低通气指数降至 5 以下。我们预计,对于轻度至中度与体位相关的阻塞性睡眠呼吸暂停患者,这种装置的体位治疗可以作为单一治疗方法应用,而对于阻塞性睡眠呼吸暂停更严重的患者,这种装置可以与其他治疗方式联合使用。

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