Faculty of Nursing, Universidad de Castilla-La Mancha, Cuenca, Spain.
Faculty of Education, Universidad de Castilla-La Mancha, Cuenca, Spain
BMJ Open. 2021 Dec 2;11(12):e049286. doi: 10.1136/bmjopen-2021-049286.
The main treatment for sleep apnoeas and hypopnoeas syndrome (SAHS) is continuous positive airway pressure (CPAP). However, patients sometimes do not adhere to the treatment protocol. Supplementary and complementary therapies have appeared as alternatives. Some of the therapies which are especially important are those related to myofunctional (MFT) and postural therapy (PT), as all of them are non-invasive, and their application is simpler than that of CPAP. We aim to present a protocol for a systematic review and meta-analysis for investigating new SAHS treatments, including the protocols and frequency of use and the effects they have on patient signs, symptoms and quality of life.
The literature search will be conducted using the Cochrane, Web of Science, Medline (via PubMed) and Scopus databases, from January 2020 to December 2020. All types of studies written in English and Spanish that investigate the use of alternative SAHS treatments related to MFT, or more importantly, the combination of MFT and PRT, will be selected. To evaluate their quality, the Critical Appraisal Checklist for Analytical Cross-Sectional will be applied. The primary factor valued in the studies will be the inclusion of MFT and PT reeducation in the treatment. Subgroup analyses will be carried out evaluating the specific type of treatments chosen and the improvements or deteriorations in the level of health and quality of life in the patients. Finally, several patient-related outcomes, namely sleep quality, quality of life and sleep Apnoeas and Hypoapnoeas Index, will be examined.
In this case, ethical approval is not necessary. The data used in the review will be exclusively obtained from published studies, implying there are no privacy concerns. The information obtained will be relevant to understand if the new treatments applied in SAHS are effective, and if postural and MFT therapy used together can be considered an appropriate approach to treat this disease.The results will be published in a peer-reviewed journal.
睡眠呼吸暂停低通气综合征(SAHS)的主要治疗方法是持续气道正压通气(CPAP)。然而,患者有时不遵守治疗方案。补充和辅助疗法已经出现作为替代方法。其中一些特别重要的疗法是与肌肉功能(MFT)和姿势疗法(PT)相关的疗法,因为它们都是非侵入性的,其应用比 CPAP 更简单。我们旨在提出一种系统评价和荟萃分析的方案,以研究新的 SAHS 治疗方法,包括使用方案和频率以及它们对患者体征、症状和生活质量的影响。
文献检索将使用 Cochrane、Web of Science、Medline(通过 PubMed)和 Scopus 数据库进行,时间范围为 2020 年 1 月至 2020 年 12 月。将选择所有以英语和西班牙语撰写的研究,调查与 MFT 相关的替代 SAHS 治疗方法的使用,或更重要的是,MFT 和 PRT 的联合使用。为了评估它们的质量,将应用分析性横断面研究的关键评估清单。研究中评估的主要因素是将 MFT 和 PT 再教育纳入治疗中。将进行亚组分析,评估所选治疗类型的具体类型以及患者健康和生活质量水平的改善或恶化。最后,将检查几个与患者相关的结果,即睡眠质量、生活质量和睡眠呼吸暂停低通气指数。
在这种情况下,不需要伦理批准。综述中使用的数据将完全从已发表的研究中获得,这意味着不存在隐私问题。获得的信息将有助于了解应用于 SAHS 的新治疗方法是否有效,以及姿势和 MFT 疗法一起使用是否可以被认为是治疗这种疾病的一种合适方法。结果将发表在同行评议的期刊上。