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Clinical evidence for neuroprotection in glaucoma.

作者信息

Cordeiro M Francesca, Levin Leonard A

出版信息

Am J Ophthalmol. 2011 Nov;152(5):715-6. doi: 10.1016/j.ajo.2011.06.015.

DOI:10.1016/j.ajo.2011.06.015
PMID:22017839
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3298033/
Abstract
摘要

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The rate of progression and ocular perfusion pressure in the Low-pressure Glaucoma Treatment Study.低压性青光眼治疗研究中的疾病进展率和眼灌注压
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Risk factors for visual field progression in the low-pressure glaucoma treatment study.低眼压性青光眼治疗研究中视野进展的风险因素。
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Caffeine administration prevents retinal neuroinflammation and loss of retinal ganglion cells in an animal model of glaucoma.在青光眼动物模型中,给予咖啡因可预防视网膜神经炎症和视网膜神经节细胞的丧失。
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Adenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressure.腺苷A2A受体阻断可预防压力升高引起的神经炎症诱导的视网膜神经节细胞死亡。
J Neuroinflammation. 2015 Jun 10;12:115. doi: 10.1186/s12974-015-0333-5.

本文引用的文献

1
A randomized trial of brimonidine versus timolol in preserving visual function: results from the Low-Pressure Glaucoma Treatment Study.一项关于溴莫尼定与噻吗洛尔对视功能保护作用的随机试验:来自低眼压性青光眼治疗研究的结果。
Am J Ophthalmol. 2011 Apr;151(4):671-81. doi: 10.1016/j.ajo.2010.09.026. Epub 2011 Jan 22.
2
Neuroprotection in glaucoma - Is there a future role?青光眼的神经保护治疗——是否有未来的作用?
Exp Eye Res. 2010 Nov;91(5):554-66. doi: 10.1016/j.exer.2010.08.009. Epub 2010 Aug 26.
3
Diurnal and nocturnal effects of brimonidine monotherapy on intraocular pressure.溴莫尼定单药治疗对眼压的昼夜影响。
Ophthalmology. 2010 Nov;117(11):2075-9. doi: 10.1016/j.ophtha.2010.03.026. Epub 2010 Jul 21.
4
Lost in translation: bumps in the road between bench and bedside.翻译之困:基础研究与临床应用之间的障碍
JAMA. 2010 Apr 21;303(15):1533-4. doi: 10.1001/jama.2010.463.
5
Neuroprotection for treatment of glaucoma in adults.用于治疗成人青光眼的神经保护。
Cochrane Database Syst Rev. 2010 Feb 17(2):CD006539. doi: 10.1002/14651858.CD006539.pub2.
6
Neuroprotection: extrapolating from neurologic diseases to the eye.神经保护:从神经系统疾病推断至眼部疾病
Am J Ophthalmol. 2009 Aug;148(2):186-191.e2. doi: 10.1016/j.ajo.2009.03.029. Epub 2009 May 23.
7
Effects of topical hypotensive drugs on circadian IOP, blood pressure, and calculated diastolic ocular perfusion pressure in patients with glaucoma.局部降压药物对青光眼患者昼夜眼压、血压及计算得出的舒张期眼灌注压的影响。
Invest Ophthalmol Vis Sci. 2006 Jul;47(7):2917-23. doi: 10.1167/iovs.05-1253.
8
Comparison of glaucomatous progression between untreated patients with normal-tension glaucoma and patients with therapeutically reduced intraocular pressures. Collaborative Normal-Tension Glaucoma Study Group.未经治疗的正常眼压性青光眼患者与经治疗眼压降低的患者之间青光眼进展情况的比较。协作性正常眼压性青光眼研究组。
Am J Ophthalmol. 1998 Oct;126(4):487-97. doi: 10.1016/s0002-9394(98)00223-2.