Cué J I, Cryer H G, Miller F B, Richardson J D, Polk H C
Department of Surgery, University of Louisville School of Medicine, KY 40292.
J Trauma. 1990 Aug;30(8):1007-11; discussion 1011-3. doi: 10.1097/00005373-199008000-00010.
We evaluated 35 consecutive patients treated with temporary intraabdominal packing for control of bleeding to determine factors that could improve hemorrhage control, morbidity from infection, and mortality. Twelve patients could not be resuscitated from hemorrhagic shock and died in the operating or recovery room. Bleeding was controlled in the remaining 23 patients; however, five (22%) died of complications other than hemorrhage. Intra-abdominal abscesses occurred in seven of the 21 patients who survived longer than 5 days and were more frequent in patients who had gastrointestinal perforation (50% versus 27%) and selective hepatic artery ligation (80% versus 19%). Four patients with either retrohepatic vena cava injury, hepatic vein injury, or both, were packed without attempted repair; three underwent delayed repair and survived. Coagulopathy occurred in 55% of patients who received greater than 15 units of blood before packing but in only 17% who received less than 15 units. The abdomens of ten patients were closed with a prosthetic mesh which did not prevent hemorrhage control, and only one patient developed a wound infection compared to 42% of patients with primary suture closure. We therefore conclude: 1) packing is more effective if instituted early (when less than 15 units of blood have been transfused) and is not contraindicated before either repair of retrohepatic vena cava injury, hepatic vein injury, or both; 2) selective hepatic artery ligation should be avoided if packing alone stops bleeding; 3) abdominal closure with a synthetic mesh decreases the incidence of wound infection; and 4) patients should be returned to the operating room for repacking if 24-hour postoperative blood requirements exceed 10 units.
我们评估了35例连续接受临时腹腔填塞以控制出血的患者,以确定可改善出血控制、感染发病率和死亡率的因素。12例患者因失血性休克未能复苏,死于手术室或恢复室。其余23例患者出血得到控制;然而,5例(22%)死于出血以外的并发症。在存活超过5天的21例患者中,7例发生腹腔脓肿,在有胃肠道穿孔的患者中更常见(50%对27%),以及选择性肝动脉结扎的患者中(80%对19%)。4例有肝后腔静脉损伤、肝静脉损伤或两者皆有的患者进行了填塞,未尝试修复;3例接受了延迟修复并存活。在填塞前接受超过15单位血液的患者中,55%发生凝血障碍,而接受少于15单位血液的患者中仅17%发生。10例患者的腹部用人工补片关闭,这并未妨碍出血控制,与一期缝合关闭的患者中42%相比,只有1例患者发生伤口感染。因此,我们得出结论:1)如果早期实施(当输血少于15单位时),填塞更有效,并且在修复肝后腔静脉损伤、肝静脉损伤或两者之前并非禁忌;2)如果单独填塞能止血,应避免选择性肝动脉结扎;3)用合成补片关闭腹部可降低伤口感染的发生率;4)如果术后24小时的血液需求量超过10单位,患者应返回手术室重新填塞。